mitosome matrix

cellstructuremech:mitosome_matrix · Membrane organelle · Subcellular region · Proposed

The matrix of a mitosome is the mitosomal internal spaces enclosed by the inner membrane. [uniprot.location:SL-0441 — Mitosome matrix]

Synonyms: mitosomal matrix

Part of: mitosome (GO:0032047)

Xrefs: uniprot.location:SL-0441 — Mitosome matrix

Taxonomic distribution

NCBITaxon:2759 Eukaryota — RARE: Mitosome matrices occur in the patchy anaerobic or microaerophilic microbial eukaryotes that retain double-membrane mitochondrion-related mitosomes. [DOI:10.1111/jeu.12922]
NCBITaxon:5759 Entamoeba histolytica — COMMON: The Entamoeba mitochondrion-related mitosome was identified as a double-membrane organelle whose internal matrix is enclosed by the inner mitosomal membrane. [DOI:10.1046/j.1365-2958.1999.01414.x]

NCBITaxon:5759 Entamoeba histolytica — Amoebozoan parasite in which mitosomes were initially described as double-membrane mitochondrion-related organelles. [DOI:10.1046/j.1365-2958.1999.01414.x]

The mitosome matrix is the internal mitosome compartment enclosed by the mitosome inner membrane.

Subject	Predicate	Object	Evidence
mitosome matrix	is part of	mitosome	`uniprot.location:SL-0441` — Mitosome matrix UniProt SL-0441 places the mitosome matrix under the mitosome subcellular location. `GO:0032047` GO:0032047 identifies the containing mitosome.
mitosome inner membrane	encloses	mitosome matrix	`uniprot.location:SL-0441` — Mitosome matrix UniProt SL-0441 defines the mitosome matrix as the internal spaces enclosed by the inner membrane. `uniprot.location:SL-0439` — Mitosome inner membrane UniProt SL-0439 defines the mitosome inner membrane by its position between the matrix and the intermembrane space.

uniprot.location:SL-0441 — Mitosome matrix UniProt Subcellular Location entry SL-0441 identifies the mitosome matrix, lists mitosomal matrix as an exact synonym, and places it under the mitosome location.
uniprot.location:SL-0439 — Mitosome inner membrane UniProt Subcellular Location entry SL-0439 identifies the inner mitosomal membrane as separating the matrix from the intermembrane space.
GO:0043233 Gene Ontology cellular-component parent term for organelle lumen.
GO:0032047 Gene Ontology cellular-component term for the containing mitosome.
DOI:10.1046/j.1365-2958.1999.01414.x Tovar et al. 1999, The mitosome, a novel organelle related to mitochondria in the amitochondrial parasite Entamoeba histolytica, Molecular Microbiology.
DOI:10.1111/jeu.12922 Tachezy 2022, Hydrogenosomes and mitosomes: Mitochondria of anaerobic eukaryotes, Journal of Eukaryotic Microbiology.

2026-09-13T20:15:32Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-13T20:16:06Z codex · EXPANDED_RECORD — Added the UniProt SL mitosomal-matrix synonym and xref, organelle-lumen parentage, mitosome parthood, rare anaerobic eukaryote and Entamoeba scope, UniProt/GO/DOI evidence, and a nonmechanistic matrix-topology graph.