phagocytic vesicle membrane

GO:0030670 · Membrane organelle · Membrane · Proposed

The lipid bilayer surrounding a phagocytic vesicle. [GO:0030670]

Synonyms: Phagosome membrane; Phagosomal membrane

Part of: phagocytic vesicle (GO:0045335)

Xrefs: uniprot.location:SL-0205 — Phagosome membrane

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
phagocytic vesicle lipid bilayer	Lipid	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Lipid-bilayer material that forms the phagocytic vesicle membrane boundary around ingested particulate cargo. `GO:0030670` GO:0030670 identifies the phagocytic vesicle membrane surrounding a phagocytic vesicle. `uniprot.location:SL-0205` — Phagosome membrane UniProt SL-0205 maps directly to GO:0030670 and describes the membrane surrounding a phagosome.

NCBITaxon:44689 Dictyostelium discoideum — COMMON: Dictyostelium discoideum phagosomes have membranes that are progressively remodeled after particle uptake. [PMID:12388753]

NCBITaxon:44689 Dictyostelium discoideum — Amoebozoan model whose purified latex-bead phagosome membranes were profiled across a maturation time course. [PMID:16926386]

phagosome maturation GO:0090382 — The phagocytic vesicle membrane is progressively remodeled as newly formed phagosomes mature toward late digestive compartments.
- GO:0090382 GO:0090382 defines phagosome maturation as cellular rearrangement of phagosome constituent parts after early phagosome formation.
- PMID:12388753 Gotthardt et al. 2002 dissected Dictyostelium phagosome maturation into temporally distinct membrane-trafficking phases.

The phagocytic vesicle membrane is part of the phagocytic vesicle, bounds the phagocytic vesicle lumen, and is remodeled during phagosome maturation.

Subject	Predicate	Object	Evidence
phagocytic vesicle membrane	bounds	phagocytic vesicle lumen	`GO:0030670` GO:0030670 identifies the membrane. `GO:0097013` GO:0097013 defines the phagocytic vesicle lumen as enclosed by a phagocytic vesicle membrane.
phagocytic vesicle membrane	is part of	phagocytic vesicle	`GO:0030670` GO:0030670 identifies the phagocytic vesicle membrane surrounding a phagocytic vesicle. `uniprot.location:SL-0205` — Phagosome membrane UniProt SL-0205 names the phagosome as the parent compartment.
phagosome maturation	remodels	phagocytic vesicle membrane	`GO:0090382` GO:0090382 defines phagosome maturation as rearrangement of phagosome parts. `PMID:12388753` Gotthardt et al. 2002 resolved ordered Dictyostelium phagosome membrane-trafficking phases.

CURATION_TODO (OPEN): Resolve an exact source-neutral grounding for the lipid constituent of the phagocytic vesicle membrane. The record is exactly grounded to GO:0030670 and UniProt SL-0205, but no exact source-neutral CURIE was curated for the generic lipid constituent of the phagocytic vesicle membrane.

GO:0030670 Gene Ontology cellular-component term for the phagocytic vesicle membrane.
GO:0030659 Gene Ontology cellular-component parent term for cytoplasmic vesicle membrane.
GO:0045335 Gene Ontology cellular-component term for the enclosing phagocytic vesicle.
GO:0097013 Gene Ontology cellular-component term for the lumen bounded by the phagocytic vesicle membrane.
GO:0090382 Gene Ontology biological-process term for phagosome maturation.
uniprot.location:SL-0205 — Phagosome membrane UniProt Subcellular Location entry SL-0205 maps to GO:0030670 and places phagosome membrane under cytoplasmic vesicle membrane.
PMID:12388753 Gotthardt et al. 2002, High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases, Molecular Biology of the Cell.
PMID:16926386 Gotthardt et al. 2006, Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake, Molecular & Cellular Proteomics.

2026-09-23T18:55:00Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-23T18:55:48Z codex · EXPANDED_RECORD — Added UniProt synonyms, cytoplasmic-vesicle membrane parentage, phagocytic-vesicle parthood, the UniProt SL-0205 xref, a reviewed-label-only lipid-bilayer component, Dictyostelium scope, GO/UniProt/PMID evidence, a phagosome-maturation function, and a nonmechanistic phagocytic-vesicle membrane topology graph.