plasma membrane-derived thylakoid lumen

GO:0031979 · Membrane organelle · Subcellular region · Proposed

The internal lumen enclosed by a plasma membrane-derived bacterial thylakoid. [GO:0031979]

Synonyms: cellular thylakoid lumen

Part of: bacterial thylakoid (GO:0030075)

Xrefs: uniprot.location:SL-0044 — Cellular thylakoid lumen

UniProt location names: UniProt Consortium, CC BY 4.0. Reference label and route sources.

Taxonomic distribution

NCBITaxon:1117 Cyanobacteriota — COMMON: The plasma membrane-derived thylakoid lumen occurs in the cyanobacteria that build internal thylakoids, but is absent from Gloeobacter-like lineages that photosynthesize only at the plasma membrane. [DOI:10.1146/annurev-cellbio-120823-022747]

Canonical examples

NCBITaxon:1148 Synechocystis sp. PCC 6803 — Cyanobacterial model used to probe de novo internal thylakoid formation and the lumenal space that those membranes enclose. [DOI:10.1038/s41467-021-23680-1]

Mechanism graphs

Bacterial thylakoid lumen topology (FUNCTION)

The plasma membrane-derived thylakoid lumen is the internal compartment of a cyanobacterial thylakoid bounded by the plasma membrane-derived thylakoid membrane.

Subject	Predicate	Object	Evidence
plasma membrane-derived thylakoid lumen	is part of	bacterial thylakoid	`GO:0031979` GO:0031979 identifies the plasma membrane-derived thylakoid lumen. `GO:0030075` GO:0030075 identifies the containing bacterial thylakoid. `uniprot.location:SL-0044` — Cellular thylakoid lumen UniProt SL-0044 places Cellular thylakoid lumen under Cellular thylakoid.
plasma membrane-derived thylakoid membrane	surrounds	plasma membrane-derived thylakoid lumen	`GO:0031676` GO:0031676 identifies the bounding plasma membrane-derived thylakoid membrane. `GO:0031979` GO:0031979 identifies the lumen enclosed by a plasma membrane-derived thylakoid.

Discussions

INTERPRETATION (RESOLVED): Avoid organelle-lumen parentage for the plasma membrane-derived thylakoid lumen. GO:0031979 denotes the internal compartment of a plasma membrane-derived bacterial thylakoid, while GO:0009579 explicitly scopes thylakoids as membranous structures that are not considered organelles.

Evidence

GO:0031979 Gene Ontology cellular-component term for the plasma membrane-derived thylakoid lumen.
GO:0030075 Gene Ontology cellular-component term for the containing bacterial thylakoid.
GO:0031676 Gene Ontology cellular-component term for the bacterial thylakoid membrane that bounds this lumen.
GO:0009579 Gene Ontology cellular-component term for thylakoid, used to scope thylakoids as non-organelle membranous structures.
uniprot.location:SL-0044 — Cellular thylakoid lumen UniProt Subcellular Location SL-0044 maps Cellular thylakoid lumen to GO:0031979 and places it under the Cellular thylakoid location.
DOI:10.1146/annurev-cellbio-120823-022747 Perez-Boerema et al. 2024 review cyanobacterial thylakoid diversity, internal thylakoid absence from Gloeobacter-like lineages, and trans-thylakoid proton-gradient generation.
DOI:10.1038/s41467-021-23680-1 Huokko et al. 2021 probed de novo thylakoid membrane biogenesis and dynamics in Synechocystis sp. PCC 6803.

Curation history

2026-09-13T00:10:17Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-13T00:11:00Z codex · EXPANDED_RECORD — Added the UniProt SL xref and synonym, bacterial thylakoid parthood, Cyanobacteriota distribution, a Synechocystis example, literature and GO evidence, a nonmechanistic lumen-topology graph, and a resolved non-organelle parentage interpretation.
2026-09-13T00:20:18Z codex · ADDRESS_REVIEW — Resolved #724 by adding GO:0030075 evidence to the resolved non-organelle parentage discussion.

Source: data/structures/membrane_organelle/plasma_membrane_derived_thylakoid_lumen.yaml