cis-Golgi network membrane

GO:0033106 · Membrane organelle · Membrane · Proposed

The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. [GO:0033106]

Synonyms: cis Golgi network membrane

Part of: cis-Golgi network (GO:0005801)

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
cis-Golgi network membrane lipid bilayer	Lipid	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Lipid-bilayer constituent of the cis-Golgi network membrane. `GO:0033106` GO:0033106 defines the cis-Golgi network membrane as the lipid bilayer around compartments that make up the cis-Golgi network.

NCBITaxon:4922 Komagataella pastoris — COMMON: Rossanese et al. resolved ordered Pichia pastoris Golgi stacks positioned near discrete transitional ER sites. [DOI:10.1083/jcb.145.1.69]

NCBITaxon:4922 Komagataella pastoris — Budding-yeast model, originally studied as Pichia pastoris, with ordered Golgi stacks associated with transitional ER organization. [DOI:10.1083/jcb.145.1.69]

The cis-Golgi network membrane bounds cis-Golgi network compartments on the Golgi side that abuts the endoplasmic reticulum.

Subject	Predicate	Object	Evidence
cis-Golgi network membrane	bounds	cis-Golgi network	`GO:0033106` GO:0033106 defines the membrane surrounding cis-Golgi network compartments.
cis-Golgi network	is part of	Golgi apparatus	`GO:0005801` GO:0005801 defines the cis-Golgi network as a network of tubular and cisternal structures on the convex side of the Golgi apparatus.
cis-Golgi network	abuts	endoplasmic reticulum	`GO:0005801` GO:0005801 places the cis-Golgi network on the Golgi side that abuts the endoplasmic reticulum. `DOI:10.1083/jcb.145.1.69` Rossanese et al. 1999 compared transitional-ER organization with Pichia and Saccharomyces Golgi organization.

CURATION_TODO (OPEN): Resolve an exact source-neutral grounding for the lipid constituent of the cis-Golgi network membrane. The record is exactly grounded to GO:0033106, but the cis-Golgi network membrane lipid-bilayer constituent is intentionally left as reviewed-label-only until an exact source-neutral lipid or membrane-constituent CURIE is curated.
INTERPRETATION (RESOLVED): Keep Sed5p and transitional-ER/COPII traffic factors out of the cis-Golgi network membrane structural-component list until exact source-neutral families are curated and a constituent-versus-trafficking boundary is reviewed. Rossanese et al. 1999 and Cho et al. 2000 support ER-proximal and Sed5p-positive early Golgi organization, but this initial membrane record does not treat those trafficking factors as lipid-bilayer constituents of the cis-Golgi network membrane itself.

GO:0033106 Gene Ontology cellular-component term for cis-Golgi network membrane.
GO:0000139 Gene Ontology cellular-component parent term for Golgi membrane.
GO:0005801 Gene Ontology cellular-component term for cis-Golgi network.
GO:0005794 Gene Ontology cellular-component term for Golgi apparatus.
GO:0005783 Gene Ontology cellular-component term for endoplasmic reticulum.
DOI:10.1083/jcb.145.1.69 Rossanese et al. 1999, 'Golgi Structure Correlates with Transitional Endoplasmic Reticulum Organization in Pichia pastoris and Saccharomyces cerevisiae', Journal of Cell Biology.
DOI:10.1016/S0014-5793(00)01268-0 Cho, Noda and Yoda 2000, 'Proteins in the early golgi compartment of Saccharomyces cerevisiae immunoisolated by Sed5p', FEBS Letters.

2026-09-14T06:27:38Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-14T06:28:22Z codex · EXPANDED_RECORD — Added Golgi-membrane parentage, cis-Golgi-network parthood, a reviewed-label-only cis-Golgi network membrane lipid-bilayer component, Komagataella scope, GO/DOI evidence, a nonmechanistic topology graph, and lipid-grounding plus early-Golgi trafficking-factor boundary discussions.