COPII-coated vesicle lumen

cellstructuremech:copii_coated_vesicle_lumen · Membrane organelle · Subcellular region · Proposed

The COPII-coated vesicle compartment bounded by the COPII-coated vesicle membrane. [uniprot.location:SL-0322 — COPII-coated vesicle lumen]

Synonyms: Coat protein complexes II lumen; ER to Golgi transport vesicle lumen

Part of: COPII-coated ER to Golgi transport vesicle (GO:0030134)

Xrefs: uniprot.location:SL-0322 — COPII-coated vesicle lumen

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast forms COPII-coated ER-to-Golgi transport vesicles from endoplasmic-reticulum membranes. [PMID:8004676]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast model in which Sec proteins were identified as COPII coat machinery that drives ER-derived vesicle budding. [PMID:8004676]

The ER to Golgi transport vesicle membrane bounds the COPII-coated vesicle lumen inside the coated carrier.

Subject	Predicate	Object	Evidence
COPII-coated vesicle lumen	is part of	COPII-coated ER to Golgi transport vesicle	`uniprot.location:SL-0322` — COPII-coated vesicle lumen UniProt SL-0322 places the COPII-coated vesicle lumen under the COPII-coated vesicle. `GO:0030134` GO:0030134 identifies the enclosing COPII-coated ER-to-Golgi transport vesicle.
ER to Golgi transport vesicle membrane	bounds	COPII-coated vesicle lumen	`uniprot.location:SL-0322` — COPII-coated vesicle lumen UniProt SL-0322 describes the lumen as bounded by the COPII-coated vesicle membrane. `GO:0012507` GO:0012507 identifies the surrounding ER to Golgi transport vesicle membrane.

uniprot.location:SL-0322 — COPII-coated vesicle lumen UniProt Subcellular Location entry SL-0322 identifies the COPII-coated vesicle lumen, places it under cytoplasmic vesicle lumen, and names it part of COPII-coated vesicle.
GO:0060205 Gene Ontology cellular-component parent term for cytoplasmic vesicle lumen.
GO:0030134 Gene Ontology cellular-component term for the enclosing COPII-coated ER-to-Golgi transport vesicle.
GO:0012507 Gene Ontology cellular-component term for the ER to Golgi transport vesicle membrane bounding the lumen.
PMID:8004676 Barlowe et al. 1994, COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum, Cell.

2026-09-14T22:18:12Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-14T22:18:47Z codex · EXPANDED_RECORD — Added UniProt synonyms, cytoplasmic-vesicle-lumen parentage, COPII-coated-vesicle parthood, the UniProt SL-0322 xref, Saccharomyces scope, GO/UniProt/DOI evidence, and a nonmechanistic COPII-coated-vesicle lumen topology graph.
2026-09-21T09:25:14Z codex · REPLACED_UNREADABLE_EVIDENCE — Resolved #1229 by routing Barlowe et al. 1994 COPII evidence through reachable PMID:8004676 instead of the unreadable Cell DOI.