cytoplasmic vesicle membrane

GO:0030659 · Membrane organelle · Membrane · Proposed

The lipid bilayer surrounding a cytoplasmic vesicle. [GO:0030659]

Part of: cytoplasmic vesicle (GO:0031410)

Xrefs: uniprot.location:SL-0089 — Cytoplasmic vesicle membrane

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
cytoplasmic vesicle membrane lipid bilayer	Lipid	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Lipid-bilayer constituent of the cytoplasmic vesicle membrane that surrounds a cytoplasmic vesicle. `GO:0030659` GO:0030659 identifies the membrane surrounding a cytoplasmic vesicle. `uniprot.location:SL-0089` — Cytoplasmic vesicle membrane UniProt Subcellular Location SL-0089 maps to GO:0030659 and denotes the cytoplasmic vesicle membrane.

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast has Cvt vesicle membranes, a double-membrane cytosolic carrier subtype of the GO cytoplasmic vesicle membrane class. [DOI:10.1091/mbc.e03-07-0479]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast model used to characterize early-secretory-pathway requirements for Cvt vesicle and autophagosome assembly. [DOI:10.1091/mbc.e03-07-0479]

The cytoplasmic vesicle membrane is the lipid-bilayer boundary of a cytoplasmic vesicle.

Subject	Predicate	Object	Evidence
cytoplasmic vesicle membrane	is part of	cytoplasmic vesicle	`GO:0030659` GO:0030659 identifies the cytoplasmic vesicle membrane. `GO:0031410` GO:0031410 identifies the containing cytoplasmic vesicle.
cytoplasmic vesicle membrane	bounds	cytoplasmic vesicle	`GO:0030659` GO:0030659 identifies the membrane surrounding a cytoplasmic vesicle. `uniprot.location:SL-0089` — Cytoplasmic vesicle membrane UniProt SL-0089 denotes the cytoplasmic vesicle membrane.

CURATION_TODO (OPEN): Resolve an exact source-neutral grounding for the lipid constituent of the cytoplasmic vesicle membrane. The record is exactly grounded to GO:0030659, but the cytoplasmic vesicle membrane lipid-bilayer constituent is intentionally left as reviewed-label-only until an exact source-neutral lipid or membrane-constituent CURIE is curated.

GO:0030659 Gene Ontology cellular-component term for the cytoplasmic vesicle membrane.
GO:0016020 Gene Ontology cellular-component parent term for cellular membranes.
GO:0031410 Gene Ontology cellular-component term for the cytoplasmic vesicle that this membrane surrounds.
uniprot.location:SL-0089 — Cytoplasmic vesicle membrane UniProt Subcellular Location entry SL-0089 maps directly to GO:0030659, places the cytoplasmic vesicle membrane under cytoplasmic vesicle and endomembrane system, and describes cytoplasmic vesicles as mediating vesicular transport among secretory and endocytic organelles.
DOI:10.1091/mbc.e03-07-0479 Reggiori et al. 2004, Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae, Molecular Biology of the Cell.

2026-09-14T20:14:24Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-14T20:15:06Z codex · EXPANDED_RECORD — Added cellular-membrane parentage, cytoplasmic-vesicle parthood, the UniProt SL xref, a reviewed-label-only lipid-bilayer component, budding-yeast scope, GO/UniProt/DOI evidence, a nonmechanistic vesicle-membrane topology graph, and a lipid-grounding TODO.
2026-09-14T20:25:19Z codex · REVIEW_FIX — Addressed issue #894 by removing an unsupported electron-microscopy method claim from the Saccharomyces cerevisiae canonical example.