cytoplasmic vesicle

GO:0031410 · Membrane organelle · Membrane bounded organelle · Proposed

A vesicle found in the cytoplasm of a cell. [GO:0031410]

Has part: cytoplasmic vesicle membrane (GO:0030659); cytoplasmic vesicle lumen (GO:0060205)

Xrefs: uniprot.location:SL-0088 — Cytoplasmic vesicle

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
cytoplasmic vesicle membrane	Lipid	part of	`GO:0030659`			ESSENTIAL	Lipid-bilayer membrane bounding the cytoplasmic vesicle. `GO:0030659` GO:0030659 identifies the membrane surrounding a cytoplasmic vesicle. `GO:0031410` GO:0031410 identifies the whole cytoplasmic vesicle containing that membrane.

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast forms cytosolic Cvt vesicles in the cytoplasm-to-vacuole targeting pathway. [DOI:10.1091/mbc.e03-07-0479]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast model used to characterize early-secretory-pathway requirements for Cvt vesicle and autophagosome assembly. [DOI:10.1091/mbc.e03-07-0479]

vesicular transport among endomembrane organelles — Cytoplasmic vesicles include coated and secretory/endocytic vesicles that mediate transport among organelles of secretory and endocytic systems.
- uniprot.location:SL-0088 — Cytoplasmic vesicle UniProt SL-0088 describes cytoplasmic vesicles as mediating vesicular transport among secretory and endocytic organelles.

A cytoplasmic vesicle is bounded by a cytoplasmic vesicle membrane and represents a carrier class for secretory/endocytic transport.

Subject	Predicate	Object	Evidence
cytoplasmic vesicle membrane	is part of	cytoplasmic vesicle	`GO:0030659` GO:0030659 identifies the cytoplasmic vesicle membrane. `GO:0031410` GO:0031410 identifies the containing cytoplasmic vesicle.
cytoplasmic vesicle	supports	vesicular transport among endomembrane organelles	`uniprot.location:SL-0088` — Cytoplasmic vesicle UniProt SL-0088 describes cytoplasmic vesicles as mediating this transport class.

INTERPRETATION (RESOLVED): Keep subtype-specific coat complexes and cargo out of the generic cytoplasmic vesicle components. UniProt SL-0088 describes coated, synaptic, secretory, and phagosome examples of the cytoplasmic vesicle class, so individual coats and cargoes identify specific subclasses rather than constituents of every cytoplasmic vesicle.

GO:0031410 Gene Ontology cellular-component term for cytoplasmic vesicles.
GO:0031982 Gene Ontology cellular-component parent term for vesicles.
GO:0030659 Gene Ontology cellular-component term for the cytoplasmic vesicle membrane.
GO:0060205 Gene Ontology cellular-component term for the cytoplasmic vesicle lumen.
uniprot.location:SL-0088 — Cytoplasmic vesicle UniProt Subcellular Location entry SL-0088 maps directly to GO:0031410 and places cytoplasmic vesicles under its broader vesicle location.
uniprot.location:SL-0089 — Cytoplasmic vesicle membrane UniProt Subcellular Location entry SL-0089 maps cytoplasmic vesicle membrane to GO:0030659 and names it part of cytoplasmic vesicle.
uniprot.location:SL-0325 — Cytoplasmic vesicle lumen UniProt Subcellular Location entry SL-0325 maps cytoplasmic vesicle lumen to GO:0060205 and names it part of cytoplasmic vesicle.
DOI:10.1091/mbc.e03-07-0479 Reggiori et al. 2004, Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae, Molecular Biology of the Cell.

2026-09-14T20:43:14Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-14T20:44:12Z codex · EXPANDED_RECORD — Added vesicle parentage, cytoplasmic vesicle membrane and lumen parts, the UniProt SL xref, a GO-grounded membrane component, Saccharomyces scope, vesicular-transport function, GO/UniProt/DOI evidence, a nonmechanistic transport-scope graph, and a resolved generic-component boundary discussion.
2026-09-14T20:52:14Z codex · FIXED_DISCUSSION_ANCHOR — Retargeted the subtype coat and cargo boundary discussion away from the generic components section so every discussion anchor resolves.