cellular bud neck
The constricted cellular region between a mother cell and its daughter bud in budding organisms. [GO:0005935]
Synonyms: bud neck
Part of: cellular bud (GO:0005933)
Has part: septin ring (GO:0005940)
Xrefs: uniprot.location:SL-0029 — Bud neck
Taxonomic distribution
NCBITaxon:4932Saccharomyces cerevisiae — COMMON: Budding yeast organizes a mother-bud neck where septins assemble during polarized bud growth and cytokinesis. [DOI:10.3389/fcell.2016.00123]
Canonical examples
NCBITaxon:4932Saccharomyces cerevisiae — Budding-yeast model in which Cdc3, Cdc10, Cdc11, Cdc12, and Shs1 septins organize at the mother-bud neck. [DOI:10.1534/genetics.107.073007]
Functions
- bud-neck cytokinesis site — The bud neck is the mother-bud cortical region where the septin ring assembles to organize budding-yeast cytokinesis.
GO:0005935GO:0005935 identifies the cellular bud neck.DOI:10.3389/fcell.2016.00123Glomb and Gronemeyer 2016 review septin organization and cytokinesis functions at the budding-yeast bud neck.
Mechanism graphs
Bud-neck septin topology (FUNCTION)
The cellular bud neck is the mother-daughter constriction where the budding-yeast septin ring assembles.
| Subject | Predicate | Object | Evidence |
|---|---|---|---|
| cellular bud neck | is part of | cellular bud |
|
| septin ring | assembles at | cellular bud neck |
|
Discussions
- INTERPRETATION (RESOLVED): Keep septin and polarisome proteins on their own structure records rather than duplicating them as cellular bud neck components. GO:0005935 and UniProt SL-0029 identify the mother-daughter neck region. The septin ring and bud-neck polarisome are localized substructures, so this regional record links the septin ring by has_part and leaves septin or polarisome protein constituents on their own records.
Evidence
GO:0005935Gene Ontology cellular-component term for the cellular bud neck.GO:0005933Gene Ontology cellular-component term for the cellular bud.GO:0005940Gene Ontology cellular-component term for the septin ring.uniprot.location:SL-0029— Bud neck UniProt Subcellular Location entry SL-0029 maps Bud neck to GO:0005935 and places the bud neck under Bud.uniprot.location:SL-0027— Bud UniProt Subcellular Location entry SL-0027 maps the parent Bud location to GO:0005933.DOI:10.1534/genetics.107.073007Iwase et al. 2007 studied Shs1/Sep7 with the Cdc3, Cdc10, Cdc11, and Cdc12 septins of the budding-yeast septin ring.DOI:10.3389/fcell.2016.00123Glomb and Gronemeyer 2016, 'Septin Organization and Functions in Budding Yeast', Frontiers in Cell and Developmental Biology.
Curation history
2026-09-15T01:03:12Zcodex · CREATED_RECORD — Scaffolded by scripts/new_record.py2026-09-15T01:03:42Zcodex · EXPANDED_RECORD — Added UniProt bud-neck synonymy and xref, cellular-bud parthood, septin-ring substructure, budding-yeast distribution and example evidence, a bud-neck cytokinesis scaffold function, GO/UniProt/DOI evidence, a nonmechanistic bud-neck septin topology graph, and a septin/polarity-factor component-boundary decision.2026-09-15T01:23:12Zcodex · ADDRESSED_REVIEW — Resolved #913 and #914 by adding the boundary-discussion resolved_date, retitling the bud-neck function as a cytokinesis-site assertion, and removing the over-broad cytokinesis marker edge from the topology graph.