tuberculous granuloma

habitatmech:PREGO.c312b0d6fc ·HOST_ASSOCIATED ·UNGROUNDED REVIEWED

An anatomical entity environment which is determined by a caseating granuloma formed in host tissue in response to infection by members of the Mycobacterium tuberculosis complex. — HabitatMech

Source attestations

Each upstream vocabulary's own account of this habitat. Assertion counts are per-source units and are not comparable across sources — GOLD counts organisms, BacDive strains, PREGO taxa.

What each upstream vocabulary says about this habitat
Source	Label / path	Assertions	Unit
PREGO	tubercle	11	TAXON

Broader habitats

anatomical entity environment ENVO:2100000

Associated taxa

Taxa reported from this habitat, which is weaker than being characteristic of it. rank is out of pool: a high rank in a pool of thousands of near-tied scores is a weak claim. Entries corroborated by a second, independent source are listed first.

Taxa reported from this habitat
Taxon	Source	Rank	Pool
Mycobacterium canetti CIPT 140070010 `NCBITaxon:1205674`	PREGO	1	11
Mycobacterium canetti CIPT 140070008 `NCBITaxon:1205675`	PREGO	2	11
Mycobacterium canetti CIPT 140060008 `NCBITaxon:1205676`	PREGO	3	11
Mycobacterium canetti CIPT 140070017 `NCBITaxon:1205677`	PREGO	4	11
Mycobacterium canetti CIPT 140070002 `NCBITaxon:1246119`	PREGO	5	11
Mycobacterium canetti CIPT 140070005 `NCBITaxon:1246120`	PREGO	6	11
Mycobacterium canetti CIPT 140070013 `NCBITaxon:1246121`	PREGO	7	11
Mycobacterium canetti CIPT 140070007 `NCBITaxon:1246634`	PREGO	8	11
Mycobacterium tuberculosis variant bovis AF2122/97 `NCBITaxon:233413`	PREGO	9	11
Mycobacterium leprae TN `NCBITaxon:272631`	PREGO	10	11
Mycobacterium tuberculosis H37Rv `NCBITaxon:83332`	PREGO	11	11

Also called

tuberclar — PREGO
tubercle — PREGO
tubercles — PREGO
tuberculous lesion — HabitatMech curation

Curation

What a curator decided about this record, and why. A record built from several source concepts can carry one decision per concept.

CONFIRM_UNGROUNDED 2026-09-10 · codex-gpt-5
Confirmed UNGROUNDED: no ontology term fits this concept. Item-level tubercle report read in full before definition authoring. The earlier disjoint decision stands: BTO:0002173 is a Schistosoma body-part homonym, and the UBERON and PO tubercle terms name generic normal anatomical protrusions and plant protuberances, while PREGO's source string points at a mycobacterial tubercle. No vendored ontology term names the infectious granulomatous lesion itself, so the record remains UNGROUNDED. Category set to HOST_ASSOCIATED because this habitat is formed within host tissue rather than an external OTHER source. (source concept habitatmech:PREGO.c312b0d6fc)
DEFINED 2026-09-10 · codex-gpt-5
Defined as 'tuberculous granuloma' under ENVO:2100000 'anatomical entity environment'. Definition authored from the record's committed deep-research report under research/habitats/, read in full; no new paid research was commissioned. The report interprets PREGO's BTO:0002173 'tubercle' source as the tuberculosis pathology sense because the PREGO synonyms include tubercle while the high-scoring taxa are dominated by Mycobacterium tuberculosis complex genomes. The BTO, UBERON, and PO tubercle terms are homonyms for schistosome bosses, normal anatomical protrusions, and plant protrusions; ENVO lacks a tuberculous granuloma or infectious lesion class, so ENVO:2100000 'anatomical entity environment' is the tightest vendored genus for a pathological host-tissue structure. The definition is intentionally restricted to Mycobacterium tuberculosis complex granulomas because the lone Mycobacterium leprae PREGO taxon is likely lexical spillover from PREGO's co-mention method rather than evidence for a leprosy lesion habitat.

Provenance

Generated by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.