TraitMech

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xylan degradation

traitmech:000113 · CLASS · REVIEWED

A biopolymer-degradation metabolism in which an organism hydrolyzes xylan, the most abundant hemicellulose, into xylose and xylo-oligosaccharides using xylanases and accessory enzymes.

Xylan degradation hydrolyzes hemicellulose to xylose

Evidence-backed causal sketch linking xylanases and accessory enzymes to xylan hydrolysis into xylose and xylo-oligosaccharides.

Xylan degradation hydrolyzes hemicellulose to xylose Interactive directed graph showing evidence-backed causal relationships for xylan degradation.

Edge evidence

  • xylanase systems enables xylan degradation RO:0002327

    Xylanase systems drive xylan depolymerization extracellularly.

    • DOI:10.1111/j.1757-1707.2009.01004.x Dodd & Cann review enzymatic deconstruction of xylan.
  • xylan degradation produces xylose METPO:2000202

    Xylan hydrolysis yields xylose and xylo-oligosaccharides.

    • DOI:10.1016/j.cbpa.2015.10.018 Cragg et al. include hemicellulose (xylan) degradation within lignocellulose breakdown across organisms.
  • carbon catabolite repression represses hemicellulase gene expression

    CCR (HPr/CcpA) represses hemicellulase gene expression when glucose is available.

    • DOI:10.1007/s00253-023-12977-4 Novak & Gardner 2024: carbon catabolite repression (HPr/CcpA) mediates glucose-dependent repression of hemicellulase expression; broad regulatory edge directly relevant to trait expression conditions.
  • CE15 glucuronoyl esterases positively regulates xylan saccharification

    CE15 glucuronoyl esterases synergistically increase xylanase saccharification of pretreated biomass.

    • DOI:10.1186/s13068-025-02639-0 Pentari et al. 2025: CE15 glucuronoyl esterases increased saccharification by xylanases (57-61 uM xylose equivalents) on pretreated lignocellulose; accessory-enzyme synergy edge.
  • CE15 glucuronoyl esterases produces aldouronic acids METPO:2000202

    CE15 glucuronoyl esterases promote GH30 glucuronoxylanase release of aldouronic acids.

    • DOI:10.1186/s13068-025-02639-0 Pentari et al. 2025: CE15 esterases led to up to three-times higher release of aldouronic acids by GH30 glucuronoxylanase.

Provenance

Source
METPO (2025-11-25)
Definition source
DOI:10.1111/j.1757-1707.2009.01004.x

Parent traits (1)

Synonyms (2)

  • xylanolytic RELATED_SYNONYM · DOI:10.1111/j.1757-1707.2009.01004.x
  • hemicellulose degradation BROAD_SYNONYM · DOI:10.1016/j.cbpa.2015.10.018

kg-microbe context

Matched 1 kg-microbe node via parent_proxy.

  • METPO:1000060 [-1.052, -1.766, -1.194, +0.291, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · PROPOSED_FROM_RESEARCH · claude

    Proposed candidate METABOLISM trait (xylan / hemicellulose degradation); sub-variant of biopolymer degradation.

  2. · CURATED_CAUSAL_GRAPH · claude

    Added evidence-backed causal graph (xylanase hydrolysis of xylan) with RO/METPO predicate groundings; promoted PROPOSED to REVIEWED.

  3. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:18222×1).

  4. · ENRICH_CAUSAL_GRAPH · claude

    Added 3 evidence-backed generic edges (5 new nodes) from the deep-research report.

  5. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1).