METABOLISM (180)

180 records

Records
Label and definitionIdentifierCategoryKindkg-microbe nodesSynonyms
2,3-butanediol fermentation

A fermentation in which microorganisms convert sugars to acetoin and 2,3-butanediol neutral end products through the butanediol pathway.

traitmech:000181METABOLISMCLASS01
3-hydroxypropionate bicycle

An autotrophic carbon-fixation pathway in which two molecules of bicarbonate are fixed via 3-hydroxypropionate and converted to glyoxylate and pyruvate. It is characteristic of the filamentous anoxygenic phototroph Chloroflexus aurantiacus.

traitmech:000023METABOLISMCLASS11
3-hydroxypropionate/4-hydroxybutyrate cycle

An autotrophic carbon-fixation pathway that fixes two molecules of bicarbonate per turn via 3-hydroxypropionate and 4-hydroxybutyrate intermediates. It operates in aerobic and microaerophilic Crenarchaeota such as Sulfolobus and Metallosphaera.

traitmech:000024METABOLISMCLASS11
Acetogenesis

A metabolism that produces acetate as the primary end product through the reduction of carbon dioxide or other carbon compounds using the Wood-Ljungdahl pathway, typically performed by acetogenic bacteria under anaerobic conditions.

METPO:1000845METABOLISMCLASS11
Aerobic respiration

A respiration in which molecular oxygen serves as the terminal electron acceptor in the electron transport chain, generating ATP through oxidative phosphorylation with water as the final product.

METPO:1000801METABOLISMCLASS12
Anaerobic respiration

A respiration in which an organism uses electron acceptors other than oxygen for energy production.

METPO:1000802METABOLISMCLASS12
Cable bacteria metabolism

A metabolism in which electrons are transferred over centimeter-scale distances through multicellular filaments.

METPO:1002003METABOLISMCLASS10
Calvin-Benson-Bassham cycle

An autotrophic carbon-fixation pathway (the reductive pentose phosphate cycle) that fixes CO2 using ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO). It is the most widespread CO2-fixation pathway, used by plants, algae, cyanobacteria, and many proteobacteria.

traitmech:000020METABOLISMCLASS12
Disproportionation

A metabolism in which a single substrate simultaneously undergoes both oxidation and reduction reactions, with part of the substrate serving as the electron donor and another part serving as the electron acceptor.

METPO:1000806METABOLISMCLASS10
Electron transfer

A metabolism in which electrons are transferred from an electron donor to an electron acceptor.

METPO:1000805METABOLISMCLASS10
Fermentation

A respiration that generates energy through the oxidation of organic compounds without using an external electron acceptor, using organic molecules as both electron donors and final electron acceptors.

METPO:1002005METABOLISMCLASS10
Homoacetogenesis

A metabolism in which acetate is produced as the sole reduced end product from reduction of CO2 via the acetyl-CoA pathway.

METPO:1000846METABOLISMCLASS12
Methanogenesis

A metabolism in which methane is produced as the primary end product through the reduction of carbon-containing compounds, formate, methanol, or acetate, exclusively performed by methanogenic archaea under strictly anaerobic conditions.

METPO:1000844METABOLISMCLASS15
Oxidative phosphorylation

A metabolism that generates ATP through the transfer of electrons from electron donors to electron acceptors via redox reactions, coupled to the pumping of protons across a membrane to create an electrochemical gradient.

METPO:1000803METABOLISMCLASS11
Substrate-level phosphorylation

A metabolism in which ATP is formed directly by transfer of a phosphoryl group from a substrate to ADP.

METPO:1000804METABOLISMCLASS10
Syntrophy

A metabolism in which the metabolism of one species is thermodynamically dependent on the removal of its products by another species.

METPO:1002006METABOLISMCLASS10
Wood-Ljungdahl pathway

An autotrophic carbon-fixation pathway (the reductive acetyl-CoA pathway) in which two molecules of CO2 are reduced and combined into acetyl-CoA. It is energetically efficient and used by acetogenic bacteria, methanogenic archaea, and some sulfate-reducing bacteria.

traitmech:000022METABOLISMCLASS11
accumulates

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism intracellularly accumulates above environmental concentration.

METPO:2000210METABOLISMOBJECT_PROPERTY10
acetoclastic methanogenesis

A methanogenesis in which acetate is split into methane and carbon dioxide.

traitmech:000191METABOLISMCLASS01
acetone-butanol-ethanol fermentation

A fermentation in which solventogenic bacteria convert organic carbon sources to organic acids and then reassimilate those acids to produce acetone, butanol, and ethanol solvents.

traitmech:000180METABOLISMCLASS02
anaerobic ammonium oxidation

An anaerobic nitrogen metabolism in which ammonium is oxidized with nitrite as the electron acceptor to form dinitrogen.

traitmech:000188METABOLISMCLASS02
anaerobic oxidation of methane

A metabolism in which methane is oxidized under anoxic conditions, classically coupled to sulfate reduction and mediated by consortia of anaerobic methanotrophic archaea (ANME) and sulfate-reducing bacteria. It is a major sink for methane in marine sediments.

traitmech:000033METABOLISMCLASS12
anoxygenic photosynthesis

A phototrophic metabolism that uses light energy with a single photosystem and bacteriochlorophyll, using electron donors other than water (e.g. H2S, H2, Fe(II), organics) and therefore not evolving oxygen. Characteristic of purple and green sulfur bacteria, Chloroflexi, and heliobacteria.

traitmech:000035METABOLISMCLASS11
aromatic compound degradation

A metabolism in which an organism catabolizes an aromatic compound, whether or not that compound is a hydrocarbon.

traitmech:000130METABOLISMCLASS01
aromatic hydrocarbon degradation

A hydrocarbon degradation in which the substrate carries at least one aromatic ring.

traitmech:000129METABOLISMCLASS01
arsenate respiration

An anaerobic respiration in which an organism uses arsenate as the terminal electron acceptor and reduces it to arsenite for energy conservation.

traitmech:000195METABOLISMCLASS02
arsenite oxidation

A metabolism in which an organism enzymatically oxidizes arsenite to arsenate as an energy-generating electron donor or detoxification substrate.

traitmech:000189METABOLISMCLASS02
assimilates

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism takes up and incorporates into cellular biomass.

METPO:2000002METABOLISMOBJECT_PROPERTY11
biopolymer degradation

A metabolism in which an organism secretes enzymes to depolymerize recalcitrant biopolymers (such as cellulose, hemicellulose, chitin, and lignin) into assimilable units for growth.

traitmech:000110METABOLISMCLASS11
builds acid from

An OBJECT_PROPERTY relating an organism to a chemical substrate from which the organism produces an acidic metabolite, lowering medium pH.

METPO:2000003METABOLISMOBJECT_PROPERTY10
builds base from

An OBJECT_PROPERTY relating an organism to a chemical substrate from which the organism produces an alkaline metabolite, raising medium pH.

METPO:2000004METABOLISMOBJECT_PROPERTY10
builds gas from

An OBJECT_PROPERTY relating an organism to a chemical substrate from which the organism produces a gaseous metabolite (e.g. CO2, H2, N2, H2S, CH4).

METPO:2000005METABOLISMOBJECT_PROPERTY10
butyric acid fermentation

A fermentation in which anaerobic bacteria convert organic substrates to butyrate as a major reduced end product while conserving energy by substrate-level phosphorylation or ion-gradient generation.

traitmech:000179METABOLISMCLASS01
capable of

A general OBJECT_PROPERTY relating an organism to a biological process or metabolic capability the organism is capable of. Intended use is predicate + class composition at assertion time, with a METPO biological-process (or GO biological-process) class as the object.

METPO:2000103METABOLISMOBJECT_PROPERTY10
carbon fixation

A metabolic process in which an organism assimilates inorganic carbon (CO2 or bicarbonate) into organic compounds (autotrophy). Six distinct natural autotrophic carbon-fixation pathways are currently recognized.

traitmech:000019METABOLISMCLASS15
cellulolysis

A biopolymer-degradation metabolism in which an organism hydrolyzes cellulose to cellodextrins and glucose using cellulase systems, sometimes organized into cellulosomes.

traitmech:000111METABOLISMCLASS12
chitinolysis

A biopolymer-degradation metabolism in which an organism hydrolyzes chitin to N-acetylglucosamine oligomers and monomers using secreted chitinases.

traitmech:000112METABOLISMCLASS12
chlorate respiration

An anaerobic respiration in which an organism uses chlorate as the terminal electron acceptor and reduces it to chloride for energy conservation.

traitmech:000198METABOLISMCLASS01
citrate fermentation

A fermentation in which citrate is the primary fermentable substrate.

traitmech:000182METABOLISMCLASS00
compartmentalizes

An OBJECT_PROPERTY relating an organism to a chemical that the organism sequesters into a specific subcellular compartment or specialised organelle.

METPO:2000212METABOLISMOBJECT_PROPERTY10
complete ammonia oxidation

A nitrification metabolism in which a single organism oxidizes ammonia via nitrite to nitrate.

traitmech:000187METABOLISMCLASS01
dark hydrogen oxidation

A metabolism in which an organism oxidizes molecular hydrogen as an electron donor for energy conservation independently of light.

traitmech:000131METABOLISMCLASS01
dark oxidation of sulfur compounds

A sulfur oxidation in which an organism oxidizes a reduced inorganic sulfur compound as an electron donor for energy conservation independently of light.

traitmech:000132METABOLISMCLASS01
degrades

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism enzymatically breaks down.

METPO:2000007METABOLISMOBJECT_PROPERTY11
denitrification

An anaerobic respiratory metabolism in which nitrate is reduced stepwise to gaseous dinitrogen via nitrite, nitric oxide, and nitrous oxide, removing fixed nitrogen from the system as gas.

traitmech:000104METABOLISMCLASS11
dicarboxylate/4-hydroxybutyrate cycle

An autotrophic carbon-fixation pathway that fixes one molecule of CO2 and one of bicarbonate per turn via a dicarboxylate stage and a 4-hydroxybutyrate stage. It operates in anaerobic and microaerophilic Crenarchaeota such as Ignicoccus and Thermoproteales.

traitmech:000025METABOLISMCLASS11
dimethyl sulfoxide respiration

An anaerobic respiration in which an organism uses dimethyl sulfoxide as the terminal electron acceptor for energy conservation.

traitmech:000201METABOLISMCLASS01
disproportionates

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism simultaneously oxidises and reduces (disproportionation), yielding both higher- and lower-oxidation-state products.

METPO:2000200METABOLISMOBJECT_PROPERTY11
dissimilatory iron reduction

An anaerobic respiratory metabolism in which an organism conserves energy for growth by coupling the oxidation of organic matter or hydrogen to the reduction of Fe(III) as a terminal electron acceptor. Characteristic of Geobacter and Shewanella, often via extracellular electron transfer.

traitmech:000031METABOLISMCLASS12
dissimilatory manganese reduction

An anaerobic respiratory metabolism in which an organism conserves energy by reducing Mn(IV) oxides to soluble Mn(II) as a terminal electron acceptor while oxidizing organic matter or hydrogen.

traitmech:000108METABOLISMCLASS11
dissimilatory metal reduction

An anaerobic respiratory metabolism in which an organism conserves energy for growth by coupling the oxidation of organic matter or hydrogen to the reduction of a metal (e.g. Fe(III), Mn(IV)) as a terminal electron acceptor.

traitmech:000039METABOLISMCLASS11
dissimilatory nitrate reduction to ammonium

An anaerobic respiratory metabolism in which nitrate is reduced via nitrite to ammonium (rather than to N2), conserving fixed nitrogen within the ecosystem. It is favored over denitrification under nitrate-limited, high-electron-donor conditions.

traitmech:000030METABOLISMCLASS12
dissimilatory sulfate reduction

An anaerobic respiratory metabolism in which an organism uses sulfate as the terminal electron acceptor, reducing it to hydrogen sulfide while oxidizing organic matter or hydrogen for energy.

traitmech:000105METABOLISMCLASS12
does not accumulate

An OBJECT_PROPERTY asserting that an organism does NOT intracellularly accumulate a given chemical entity above environmental concentration. Negation companion of the positive 'accumulates' predicate. The intended use is predicate + class composition at assertion time, e.g. `<organism> <this property> <CHEBI class>`.

METPO:2000230METABOLISMOBJECT_PROPERTY10
does not assimilate

An OBJECT_PROPERTY asserting that an organism does NOT take up and incorporate a given chemical entity into cellular biomass. Negation companion of the positive 'assimilates' predicate.

METPO:2000027METABOLISMOBJECT_PROPERTY11
does not build acid from

An OBJECT_PROPERTY asserting that an organism does NOT produce an acidic metabolite from a given chemical substrate (no medium acidification observed). Negation companion of 'builds acid from'.

METPO:2000028METABOLISMOBJECT_PROPERTY11
does not build base from

An OBJECT_PROPERTY asserting that an organism does NOT produce an alkaline metabolite from a given chemical substrate (no medium alkalinisation observed). Negation companion of 'builds base from'.

METPO:2000029METABOLISMOBJECT_PROPERTY11
does not build gas from

An OBJECT_PROPERTY asserting that an organism does NOT produce a gaseous metabolite from a given chemical substrate. Negation companion of 'builds gas from'.

METPO:2000030METABOLISMOBJECT_PROPERTY11
does not compartmentalize

An OBJECT_PROPERTY asserting that an organism does NOT sequester a given chemical into a specific subcellular compartment. Negation companion of 'compartmentalizes'.

METPO:2000232METABOLISMOBJECT_PROPERTY10
does not degrade

An OBJECT_PROPERTY asserting that an organism does NOT enzymatically break down a given chemical substrate. Negation companion of 'degrades'.

METPO:2000033METABOLISMOBJECT_PROPERTY11
does not disproportionate

An OBJECT_PROPERTY asserting that an organism does NOT carry out a disproportionation reaction on a given chemical substrate. Negation companion of 'disproportionates'.

METPO:2000220METABOLISMOBJECT_PROPERTY11
does not export

An OBJECT_PROPERTY asserting that an organism does NOT export a given chemical from the cytoplasm. Negation companion of 'exports'.

METPO:2000229METABOLISMOBJECT_PROPERTY10
does not ferment

An OBJECT_PROPERTY asserting that an organism does NOT ferment a given chemical substrate. Negation companion of 'ferments'.

METPO:2000037METABOLISMOBJECT_PROPERTY11
does not hydrolyze

An OBJECT_PROPERTY asserting that an organism does NOT hydrolyse a given chemical substrate. Negation companion of 'hydrolyzes'.

METPO:2000039METABOLISMOBJECT_PROPERTY11
does not import

An OBJECT_PROPERTY asserting that an organism does NOT import a given chemical from the extracellular environment. Negation companion of 'imports'.

METPO:2000228METABOLISMOBJECT_PROPERTY10
does not oxidize

An OBJECT_PROPERTY asserting that an organism does NOT oxidise a given chemical substrate. Negation companion of 'oxidizes'.

METPO:2000042METABOLISMOBJECT_PROPERTY11
does not produce

An OBJECT_PROPERTY asserting that an organism does NOT produce a given chemical as a metabolic product. Negation companion of 'produces'.

METPO:2000222METABOLISMOBJECT_PROPERTY11
does not reduce

An OBJECT_PROPERTY asserting that an organism does NOT reduce a given chemical substrate. Negation companion of 'reduces'.

METPO:2000044METABOLISMOBJECT_PROPERTY11
does not sequester

An OBJECT_PROPERTY asserting that an organism does NOT sequester or chelate a given chemical. Negation companion of 'sequesters'.

METPO:2000231METABOLISMOBJECT_PROPERTY10
does not show activity of

An OBJECT_PROPERTY asserting that an organism does NOT show the catalytic activity of a given enzyme (material entity) class. Negation companion of 'shows activity of'. Intended use is predicate + class composition at assertion time with a METPO enzyme class (METPO:1000527 or its subclass) as the object.

METPO:2000303METABOLISMOBJECT_PROPERTY11
does not transport

An OBJECT_PROPERTY asserting that an organism does NOT transport a given chemical across its membranes. Negation companion of 'transports'.

METPO:2000227METABOLISMOBJECT_PROPERTY10
does not use as carbon source

An OBJECT_PROPERTY asserting that an organism does *not* use a given chemical entity as a source of carbon for biosynthesis. The intended use is predicate + class composition at assertion time, e.g. `<organism> METPO:2000031 CHEBI:17234` ("organism does not use glucose as carbon source"). Negation companion to METPO:2000006.

METPO:2000031METABOLISMOBJECT_PROPERTY11
does not use as electron acceptor

An OBJECT_PROPERTY asserting that an organism does *not* use a given chemical entity as a terminal electron acceptor in respiration. The intended use is predicate + class composition at assertion time, e.g. `<organism> METPO:X CHEBI:17632` ("organism does not use nitrate as electron acceptor"). Negation companion to METPO:2000008.

METPO:2000034METABOLISMOBJECT_PROPERTY11
does not use as electron donor

An OBJECT_PROPERTY asserting that an organism does *not* use a given chemical entity as an electron donor. The intended use is predicate + class composition at assertion time, e.g. `<organism> METPO:X CHEBI:18276` ("organism does not use H2 as electron donor"). Negation companion to METPO:2000009.

METPO:2000035METABOLISMOBJECT_PROPERTY11
does not use as energy source

An OBJECT_PROPERTY asserting that an organism does NOT use a given chemical as a source of energy for metabolism. Negation companion of 'uses as energy source'.

METPO:2000036METABOLISMOBJECT_PROPERTY11
does not use as nitrogen source

An OBJECT_PROPERTY asserting that an organism does NOT use a given chemical as a source of nitrogen for biosynthesis. Negation companion of 'uses as nitrogen source'.

METPO:2000040METABOLISMOBJECT_PROPERTY11
does not use as sulfur source

An OBJECT_PROPERTY asserting that an organism does NOT use a given chemical as a source of sulfur for biosynthesis. Negation companion of 'uses as sulfur source'.

METPO:2000047METABOLISMOBJECT_PROPERTY11
does not use for aerobic catabolization

An OBJECT_PROPERTY asserting that an organism does NOT catabolise a given substrate under aerobic conditions. Negation companion of 'uses for aerobic catabolization'.

METPO:2000021METABOLISMOBJECT_PROPERTY11
does not use for aerobic growth

An OBJECT_PROPERTY asserting that an organism does NOT grow under aerobic conditions using a given chemical. Negation companion of 'uses for aerobic growth'.

METPO:2000022METABOLISMOBJECT_PROPERTY11
does not use for anaerobic catabolization

An OBJECT_PROPERTY asserting that an organism does NOT catabolise a given substrate under anaerobic conditions. Negation companion of 'uses for anaerobic catabolization'.

METPO:2000023METABOLISMOBJECT_PROPERTY11
does not use for anaerobic growth

An OBJECT_PROPERTY asserting that an organism does NOT grow under anaerobic conditions using a given chemical. Negation companion of 'uses for anaerobic growth'.

METPO:2000024METABOLISMOBJECT_PROPERTY11
does not use for anaerobic growth in the dark

An OBJECT_PROPERTY asserting that an organism does NOT grow under anaerobic conditions without illumination using a given chemical. Negation companion of 'uses for anaerobic growth in the dark'.

METPO:2000025METABOLISMOBJECT_PROPERTY11
does not use for anaerobic growth with light

An OBJECT_PROPERTY asserting that an organism does NOT grow under anaerobic conditions with illumination using a given chemical. Negation companion of 'uses for anaerobic growth with light'.

METPO:2000026METABOLISMOBJECT_PROPERTY11
does not use for growth

An OBJECT_PROPERTY asserting that an organism does NOT grow on a given chemical. Negation companion of 'uses for growth'.

METPO:2000038METABOLISMOBJECT_PROPERTY11
does not use for respiration

An OBJECT_PROPERTY asserting that an organism does NOT use a given chemical in respiratory metabolism. Negation companion of 'uses for respiration'.

METPO:2000046METABOLISMOBJECT_PROPERTY11
does not use in other way

Catch-all negation OBJECT_PROPERTY asserting that an organism does NOT use a given chemical in any way not covered by the more specific predicates. Negation companion of 'uses in other way'.

METPO:2000041METABOLISMOBJECT_PROPERTY11
enzyme activity analyzed

An OBJECT_PROPERTY relating an organism to an enzyme (material entity) whose catalytic activity has been experimentally assayed for that organism. Intended use is predicate + class composition at assertion time with a METPO enzyme class (METPO:1000527 or its subclass) as the object.

METPO:2000301METABOLISMOBJECT_PROPERTY11
ethanol fermentation

A fermentation in which pyruvate is decarboxylated to acetaldehyde (releasing CO2) and then reduced by NADH to ethanol, regenerating NAD+ for glycolysis. Characteristic of yeasts and the bacterium Zymomonas mobilis.

traitmech:000028METABOLISMCLASS12
exports

An OBJECT_PROPERTY relating an organism to a chemical that the organism exports from the cytoplasm to the periplasm or extracellular environment.

METPO:2000209METABOLISMOBJECT_PROPERTY10
fermentative hydrogen production

A fermentation in which an organism disposes of excess reducing equivalents by producing molecular hydrogen (H2), typically via hydrogenases acting on reduced ferredoxin or formate.

traitmech:000109METABOLISMCLASS11
ferments

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism ferments — using organic compounds as both electron donors and acceptors with substrate-level phosphorylation for ATP.

METPO:2000011METABOLISMOBJECT_PROPERTY11
fumarate respiration

An anaerobic respiration in which an organism uses fumarate as the terminal electron acceptor and reduces it to succinate for energy conservation.

traitmech:000196METABOLISMCLASS01
has NaCl delta observation

Relates a microbe to a NaCl tolerance breadth (delta) observation.

METPO:2000510METABOLISMOBJECT_PROPERTY10
has NaCl observation

Relates a microbe to a NaCl observation.

METPO:2000506METABOLISMOBJECT_PROPERTY10
has growth NaCl observation

Relates a microbe to a growth NaCl observation.

METPO:2000508METABOLISMOBJECT_PROPERTY10
has growth oxygen observation

Relates a microbe to a growth oxygen observation.

METPO:2000514METABOLISMOBJECT_PROPERTY10
has growth pH observation

Relates a microbe to a growth pH observation.

METPO:2000502METABOLISMOBJECT_PROPERTY10
has growth temperature observation

Relates a microbe to a growth temperature observation.

METPO:2000054METABOLISMOBJECT_PROPERTY10
has observation

METPO:2000511METABOLISMOBJECT_PROPERTY10
has optimum NaCl observation

Relates a microbe to an optimum NaCl observation.

METPO:2000507METABOLISMOBJECT_PROPERTY10
has optimum oxygen observation

Relates a microbe to an optimum oxygen observation.

METPO:2000513METABOLISMOBJECT_PROPERTY10
has optimum pH observation

Relates a microbe to an optimum pH observation.

METPO:2000501METABOLISMOBJECT_PROPERTY10
has optimum temperature observation

Relates a microbe to an optimum temperature observation.

METPO:2000053METABOLISMOBJECT_PROPERTY10
has oxygen delta observation

Relates a microbe to a oxygen tolerance breadth (delta) observation.

METPO:2000516METABOLISMOBJECT_PROPERTY10
has oxygen observation

Relates a microbe to an oxygen observation.

METPO:2000512METABOLISMOBJECT_PROPERTY10
has pH delta observation

Relates a microbe to a pH tolerance breadth (delta) observation.

METPO:2000504METABOLISMOBJECT_PROPERTY10
has pH observation

Relates a microbe to a pH observation.

METPO:2000239METABOLISMOBJECT_PROPERTY10
has phenotype

METPO:2000102METABOLISMOBJECT_PROPERTY10
has quality

METPO:2000101METABOLISMOBJECT_PROPERTY10
has range NaCl observation

Relates a microbe to a growth NaCl range observation.

METPO:2000509METABOLISMOBJECT_PROPERTY10
has range oxygen observation

Relates a microbe to a growth oxygen range observation.

METPO:2000515METABOLISMOBJECT_PROPERTY10
has range pH observation

Relates a microbe to a growth pH range observation.

METPO:2000503METABOLISMOBJECT_PROPERTY10
has range temperature observation

Relates a microbe to a growth temperature range observation.

METPO:2000055METABOLISMOBJECT_PROPERTY10
has temperature delta observation

Relates a microbe to a temperature tolerance breadth (delta) observation.

METPO:2000056METABOLISMOBJECT_PROPERTY10
has temperature observation

Relates a microbe to a temperature observation.

METPO:2000052METABOLISMOBJECT_PROPERTY10
hydrocarbon degradation

A metabolism in which an organism catabolizes a hydrocarbon, using it as a carbon and energy source.

traitmech:000128METABOLISMCLASS01
hydrogenotrophic methanogenesis

A methanogenesis in which carbon dioxide is reduced to methane using molecular hydrogen as the electron donor.

traitmech:000127METABOLISMCLASS02
hydrolyzes

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism hydrolyses (cleaves by addition of water).

METPO:2000013METABOLISMOBJECT_PROPERTY11
imports

An OBJECT_PROPERTY relating an organism to a chemical that the organism imports from the extracellular environment into the cytoplasm.

METPO:2000208METABOLISMOBJECT_PROPERTY10
iodate respiration

An anaerobic respiration in which an organism uses iodate as the terminal electron acceptor for energy conservation.

traitmech:000203METABOLISMCLASS01
iron oxidation

A metabolism in which an organism oxidizes ferrous iron (Fe2+) to ferric iron (Fe3+) to conserve energy, at acidic or circumneutral pH and under aerobic or anaerobic conditions.

traitmech:000107METABOLISMCLASS11
is not required for growth

An OBJECT_PROPERTY relating an organism to a chemical entity that is *not* required for that organism's growth (positive assertion of non-requirement). Functions as the negation companion of 'requires for growth'.

METPO:2000045METABOLISMOBJECT_PROPERTY11
lactic acid fermentation

A fermentation in which sugars are converted mainly to lactate, with ATP generated by substrate-level phosphorylation. Homolactic fermentation yields ~2 lactate per glucose via glycolysis; heterolactic fermentation also yields ethanol/acetate and CO2. Characteristic of lactic acid bacteria (e.g. Lactobacillus, Lactococcus).

traitmech:000026METABOLISMCLASS11
lignin degradation

A biopolymer-degradation metabolism in which an organism breaks down lignin, the recalcitrant aromatic heteropolymer of plant cell walls, using oxidative enzymes such as peroxidases and laccases.

traitmech:000114METABOLISMCLASS13
lipolysis

A metabolism in which a microorganism hydrolyzes triacylglycerols into fatty acids and glycerol through lipase-catalyzed ester cleavage.

traitmech:000190METABOLISMCLASS00
manganese oxidation

A metabolism in which microorganisms oxidize soluble Mn(II) to Mn(III) or Mn(IV) products through mechanisms including bacterial multicopper oxidases and fungal manganese peroxidases; many systems deposit insoluble manganese oxides.

traitmech:000032METABOLISMCLASS11
metabolism

A biological process that maintains life in an organism.

METPO:1000060METABOLISMCLASS10
methanol oxidation

A metabolism in which an organism oxidizes methanol, typically to formaldehyde, as a carbon and energy source.

traitmech:000133METABOLISMCLASS01
methyl-based methanogenesis

A methanogenesis in which methylated compounds donate methyl groups that are transferred to coenzyme M and reduced to methane.

traitmech:000192METABOLISMCLASS02
mixed-acid fermentation

A fermentation in which sugars are converted via the glycolytic pathway to a mixture of acids (lactic, acetic, formic, succinic) plus ethanol, CO2 and H2. Characteristic of enteric bacteria such as Escherichia coli.

traitmech:000027METABOLISMCLASS10
nitrate reduction

A metabolism in which an organism reduces nitrate, whether for energy conservation or for assimilation into biomass.

traitmech:000134METABOLISMCLASS01
nitrate respiration

A nitrogen respiration in which nitrate is the terminal electron acceptor, reduced to nitrite or further reduced products.

traitmech:000122METABOLISMCLASS01
nitrification

A biological process in which ammonia is oxidized to nitrite (ammonia oxidation) and nitrite is oxidized to nitrate (nitrite oxidation), in two steps.

METPO:1005001METABOLISMCLASS00
nitrite respiration

A nitrogen respiration in which nitrite is the terminal electron acceptor.

traitmech:000123METABOLISMCLASS01
nitrogen fixation

A metabolism in which an organism reduces atmospheric dinitrogen (N2) to ammonia using the nitrogenase enzyme complex, making fixed nitrogen biologically available (diazotrophy).

traitmech:000103METABOLISMCLASS11
nitrogen respiration

An anaerobic respiration in which an organism conserves energy by transferring electrons to an oxidized nitrogen compound as the terminal electron acceptor.

traitmech:000121METABOLISMCLASS01
organism interacts with chemical

The root OBJECT_PROPERTY for all organism-to-chemical interactions in the metabolism vocabulary; concrete uses (uses-as-X, ferments, produces, etc.) specialise this relation.

METPO:2000001METABOLISMOBJECT_PROPERTY10
organohalide respiration

An anaerobic respiration in which an organism uses an organohalide as the terminal electron acceptor for energy conservation.

traitmech:000204METABOLISMCLASS00
oxidizes

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism oxidises (removes electrons or hydrogens from).

METPO:2000016METABOLISMOBJECT_PROPERTY11
oxygenic photosynthesis

A phototrophic metabolism that uses light energy to fix CO2, oxidizing water as the electron donor and releasing molecular oxygen. It uses two linked photosystems and chlorophyll, and is characteristic of cyanobacteria (and plant chloroplasts).

traitmech:000034METABOLISMCLASS11
pectin degradation

A biopolymer-degradation metabolism in which an organism depolymerizes pectin into oligogalacturonides and catabolizes the released pectin breakdown products using pectinolytic enzymes.

traitmech:000135METABOLISMCLASS04
perchlorate respiration

An anaerobic respiration in which an organism uses perchlorate as the terminal electron acceptor and reduces it to chloride for energy conservation.

traitmech:000197METABOLISMCLASS01
photoferrotrophy

A metabolism in which anoxygenic phototrophs use light energy to oxidize Fe(II) as an electron donor for carbon fixation and biomass formation.

traitmech:000193METABOLISMCLASS02
photosynthesis

A phototrophic metabolism that uses light energy and chlorophyll- or bacteriochlorophyll-based photochemical reaction centers to drive electron flow, fixing CO2 and/or generating reducing power. Subdivided into oxygenic and anoxygenic photosynthesis.

traitmech:000038METABOLISMCLASS10
phototrophy

A metabolism in which an organism captures light as its energy source. It encompasses chlorophyll-based photosynthesis (with photochemical reaction centers) and retinal-based (rhodopsin) light-driven ion pumping.

traitmech:000037METABOLISMCLASS11
produces

An OBJECT_PROPERTY relating an organism to a chemical that the organism produces and exports or accumulates as a metabolic product.

METPO:2000202METABOLISMOBJECT_PROPERTY10
propionic acid fermentation

A fermentation that produces propionate (with acetate and CO2) from sugars or lactate, typically via the Wood-Werkman (methylmalonyl-CoA) pathway. Characteristic of propionibacteria (e.g. Propionibacterium freudenreichii).

traitmech:000029METABOLISMCLASS11
proteolysis

A biopolymer-degradation metabolism in which an organism secretes proteases to hydrolyze extracellular proteins and peptides into amino acids and short peptides for nutrition.

traitmech:000116METABOLISMCLASS12
proteorhodopsin phototrophy

A light-harvesting metabolism in which a retinal-containing membrane protein (proteorhodopsin) acts as a light-driven proton pump, generating proton motive force without chlorophyll-based reaction centers. Widespread among marine bacterioplankton.

traitmech:000036METABOLISMCLASS11
reduces

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism reduces (adds electrons or hydrogens to).

METPO:2000017METABOLISMOBJECT_PROPERTY11
reductive tricarboxylic acid cycle

An autotrophic carbon-fixation pathway (reductive citric acid / Arnon-Buchanan cycle) that runs the tricarboxylic acid cycle in reverse to fix CO2. It operates in anaerobic and microaerophilic bacteria such as green sulfur bacteria (Chlorobium) and Aquificales.

traitmech:000021METABOLISMCLASS18
requires for growth

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism requires for growth (essential nutrient, cofactor, or growth factor).

METPO:2000018METABOLISMOBJECT_PROPERTY11
respiration

A metabolism that is characterized by the method of performing cellular respiration, distinguished primarily by the specific terminal electron acceptor utilized for producing cellular energy.

METPO:1000800METABOLISMCLASS11
respiration of sulfur compounds

An anaerobic respiration in which an organism conserves energy by transferring electrons to an inorganic sulfur compound as the terminal electron acceptor.

traitmech:000124METABOLISMCLASS01
selenate respiration

An anaerobic respiration in which an organism uses selenate as the terminal electron acceptor for energy conservation.

traitmech:000202METABOLISMCLASS01
sequesters

An OBJECT_PROPERTY relating an organism to a chemical that the organism specifically sequesters or chelates intracellularly or in specialised structures.

METPO:2000211METABOLISMOBJECT_PROPERTY10
shows activity of

An OBJECT_PROPERTY relating an organism to an enzyme (material entity) for which the organism shows the corresponding catalytic activity. Intended use is predicate + class composition at assertion time with a METPO enzyme class (METPO:1000527 or its subclass) as the object — the assertion reads "<organism> expresses an enzyme of class <X>, evidenced by activity measurement".

METPO:2000302METABOLISMOBJECT_PROPERTY11
starch degradation

A biopolymer-degradation metabolism in which an organism hydrolyzes starch (amylose and amylopectin) to maltooligosaccharides and glucose using amylases and related glycoside hydrolases.

traitmech:000115METABOLISMCLASS13
sulfur oxidation

A metabolism in which an organism oxidizes reduced inorganic sulfur compounds (sulfide, elemental sulfur, thiosulfate) to sulfate, conserving energy and often supporting chemolithotrophic growth.

traitmech:000106METABOLISMCLASS11
sulfur respiration

A respiration of sulfur compounds in which elemental sulfur is the terminal electron acceptor and is reduced to sulfide.

traitmech:000125METABOLISMCLASS01
tetrathionate respiration

An anaerobic respiration in which an organism uses tetrathionate as the terminal electron acceptor and reduces it to thiosulfate for energy conservation.

traitmech:000200METABOLISMCLASS00
thiosulfate respiration

A respiration of sulfur compounds in which thiosulfate is the terminal electron acceptor.

traitmech:000126METABOLISMCLASS01
transports

An OBJECT_PROPERTY relating an organism to a chemical that the organism transports across its membranes (without specifying direction or coupling).

METPO:2000207METABOLISMOBJECT_PROPERTY10
trimethylamine N-oxide respiration

An anaerobic respiration in which an organism uses trimethylamine N-oxide as the terminal electron acceptor and reduces it to trimethylamine for energy conservation.

traitmech:000199METABOLISMCLASS01
uses as carbon source

An OBJECT_PROPERTY relating an organism to a chemical entity (e.g. a CHEBI class) that the organism uses as a source of carbon for biosynthesis. The intended use is predicate + class composition at assertion time, e.g. `<organism> METPO:2000006 CHEBI:17234` ("organism uses glucose as carbon source").

METPO:2000006METABOLISMOBJECT_PROPERTY11
uses as electron acceptor

An OBJECT_PROPERTY relating an organism to a chemical entity (e.g. a CHEBI class) that the organism uses as the terminal electron acceptor in respiration. The intended use is predicate + class composition at assertion time, e.g. `<organism> METPO:2000008 CHEBI:17632` ("organism uses nitrate as electron acceptor").

METPO:2000008METABOLISMOBJECT_PROPERTY11
uses as electron donor

An OBJECT_PROPERTY relating an organism to a chemical entity (e.g. a CHEBI class) that the organism oxidises as an electron donor for energy conservation or biosynthetic reductant. The intended use is predicate + class composition at assertion time, e.g. `<organism> METPO:2000009 CHEBI:18276` ("organism uses molecular hydrogen as electron donor").

METPO:2000009METABOLISMOBJECT_PROPERTY11
uses as energy source

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism uses as a source of energy for metabolism.

METPO:2000010METABOLISMOBJECT_PROPERTY11
uses as nitrogen source

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism uses as a source of nitrogen for biosynthesis.

METPO:2000014METABOLISMOBJECT_PROPERTY11
uses as sulfur source

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism uses as a source of sulfur for biosynthesis.

METPO:2000020METABOLISMOBJECT_PROPERTY11
uses for aerobic catabolization

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism catabolises under aerobic (oxygen-respiring) conditions.

METPO:2000032METABOLISMOBJECT_PROPERTY11
uses for aerobic growth

An OBJECT_PROPERTY relating an organism to a chemical that supports the organism's growth under aerobic conditions.

METPO:2000043METABOLISMOBJECT_PROPERTY11
uses for anaerobic catabolization

An OBJECT_PROPERTY relating an organism to a chemical substrate that the organism catabolises under anaerobic conditions.

METPO:2000048METABOLISMOBJECT_PROPERTY11
uses for anaerobic growth

An OBJECT_PROPERTY relating an organism to a chemical that supports the organism's growth under anaerobic conditions.

METPO:2000049METABOLISMOBJECT_PROPERTY11
uses for anaerobic growth in the dark

An OBJECT_PROPERTY relating an organism to a chemical that supports the organism's growth under anaerobic conditions without illumination (i.e. excluding phototrophic anaerobic growth).

METPO:2000050METABOLISMOBJECT_PROPERTY11
uses for anaerobic growth with light

An OBJECT_PROPERTY relating an organism to a chemical that supports the organism's growth under anaerobic conditions with illumination (anoxygenic phototrophic growth).

METPO:2000051METABOLISMOBJECT_PROPERTY11
uses for growth

An OBJECT_PROPERTY relating an organism to a chemical that supports the organism's growth (without specifying aerobic or anaerobic mode).

METPO:2000012METABOLISMOBJECT_PROPERTY11
uses for respiration

An OBJECT_PROPERTY relating an organism to a chemical entity that the organism uses in respiratory metabolism (typically as electron donor or terminal electron acceptor).

METPO:2000019METABOLISMOBJECT_PROPERTY11
uses in other way

A catch-all OBJECT_PROPERTY relating an organism to a chemical the organism uses in some way not covered by the more specific predicates (uses_as_carbon_source, uses_as_electron_donor, etc.).

METPO:2000015METABOLISMOBJECT_PROPERTY11
xylan degradation

A biopolymer-degradation metabolism in which an organism hydrolyzes xylan, the most abundant hemicellulose, into xylose and xylo-oligosaccharides using xylanases and accessory enzymes.

traitmech:000113METABOLISMCLASS15