dissimilatory sulfate reduction

Edge evidence

• sulfate oxidized to sulfide METPO:2007405

  Sulfate is reduced stepwise to sulfide.

  • DOI:10.1038/nrmicro1892 Muyzer & Stams review sulfate-reducing bacteria respiring sulfate to sulfide.
• dissimilatory sulfate reduction participates in anaerobic respiration biolink:participates_in

  Sulfate respiration is a major form of anaerobic respiration.

  • DOI:10.3389/fmicb.2011.00081 Plugge et al. review the metabolic flexibility of sulfate-reducing bacteria within anaerobic respiration.
• sulfate activated by ATP sulfurylase (Sat)

  Sulfate is activated by ATP sulfurylase (Sat).

  • DOI:10.3390/antiox12030767 Sulfate is taken up and activated by the enzyme ATP sulfurylase (Sat) to form APS.
• ATP sulfurylase (Sat) produces adenosine-5′-phosphosulfate (APS) METPO:2000202

  Sat activates sulfate to form APS.

  • DOI:10.3390/antiox12030767 Activated by ATP sulfurylase (Sat) to form adenosine-5′-phosphosulfate (APS).
• APS reductase AprAB reduces adenosine-5′-phosphosulfate (APS) METPO:2000017

  APS reductase AprAB reduces APS to sulfite.

  • DOI:10.1038/s41396-023-01477-y The APS reductase AprAB reduces APS to sulfite, serving as substrate of the Dsr cascade.
• APS reductase AprAB produces sulfite METPO:2000202

  AprAB reduction of APS yields sulfite.

  • DOI:10.1038/s41396-023-01477-y APS is reduced to sulfite serving as substrate of the Dsr cascade.
• DsrAB with DsrC produces DsrC-trisulfide METPO:2000202

  DsrAB produces a DsrC-trisulfide from sulfite and DsrC.

  • DOI:10.1038/s41396-023-01477-y DsrAB produces a DsrC-trisulfide from sulfite and the DsrC protein.
• DsrMK(JOP) membrane complex reduces DsrC-trisulfide METPO:2000017

  DsrMK(JOP) reduces the DsrC-trisulfide, recycling DsrC and releasing sulfide with energy conservation.

  • DOI:10.1038/s41396-023-01477-y DsrC-trisulfide is reduced by the DsrMK(JOP) membrane complex recycling DsrC and releasing sulfide while coupling to energy conservation.
• DsrMK(JOP) membrane complex produces sulfide METPO:2000202

  Terminal reduction of the DsrC-trisulfide releases sulfide.

  • DOI:10.1038/s41396-023-01477-y DsrMK(JOP) reduction releases sulfide while coupling this reduction to energy conservation.
• DsrAB with DsrC marker for sulfate/sulfite-reducing microorganisms

  The dissimilatory sulfite reductase encoded by dsrAB is a hallmark of sulfate/sulfite-reducing microorganisms.

  • DOI:10.1093/femsre/fuad058 A hallmark of SRM is the dissimilatory sulfite reductase encoded by the genes dsrAB.