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perchlorate respiration

traitmech:000197 · CLASS · PROPOSED

An anaerobic respiration in which an organism uses perchlorate as the terminal electron acceptor and reduces it to chloride for energy conservation.

Trait evidence (2)

  • DOI:10.1186/s12864-015-2011-5
    reduction to chlorite (ClO2-) in the bacterial periplasm by perchlorate reductase, and the dismutation of chlorite to chloride and molecular oxygen

    Melnyk et al. describe the canonical perchlorate-to-chloride respiratory pathway through perchlorate reductase and chlorite dismutase.

  • DOI:10.1128/AEM.05758-11
    perchlorate reductase and chlorite dismutase, which are encoded by the pcrABCD and cld genes

    Melnyk et al. support the PcrABCD and Cld gene modules as the two pathway-specific enzyme systems for perchlorate reduction to chloride.

Provenance

Identifier source
TraitMech local identifier
Definition source
DOI:10.1038/nrmicro926

Parent traits (1)

Synonyms (1)

  • dissimilatory perchlorate reduction RELATED_SYNONYM · DOI:10.1186/s12864-015-2011-5

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for organism-level perchlorate respiration before adding a TraitRecord xref.

CURATION TODO OPEN perchlorate-respiration-xref-gap · raised by codex · 2026-09-15

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

The pinned METPO snapshot contains only obsolete (Per)chlorate respiration, Perchlorate respiration, and Perchlorate-reducing classes. Candidate GO, EC, and protein-family terms for perchlorate reductase and chlorite dismutase are narrower than the whole-organism anaerobic respiration phenotype and should be checked separately before grounding PcrABCD- or Cld-level causal nodes.

Curation history

  1. · MINTED_TRAITMECH_ID · codex

    Minted perchlorate respiration as a DOI-backed anaerobic respiration TraitRecord after a repository-wide duplicate review covering ignored and hidden files; the local METPO snapshot has only obsolete perchlorate respiration classes and the replacement placeholder is reserved in proposals/metpo_traitmech_v74.