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arsenate respiration

traitmech:000195 · CLASS · PROPOSED

An anaerobic respiration in which an organism uses arsenate as the terminal electron acceptor and reduces it to arsenite for energy conservation.

Trait evidence (3)

  • DOI:10.1073/pnas.1834303100
    can be used by microorganisms as a terminal electron acceptor in anaerobic respiration

    Saltikov and Newman define the organism-level scope as microbial anaerobic respiration using arsenate, As(V), as a terminal electron acceptor.

  • DOI:10.1128/AEM.69.5.2800-2809.2003
    This gram-negative strain stoichiometrically couples the oxidation of lactate to acetate with the reduction of As(V) to arsenite

    Saltikov et al. isolated and characterized ANA-3 as a facultatively anaerobic As(V)-respiring Shewanella strain.

  • DOI:10.1128/JB.01110-07
    the Shewanella sp. strain ANA-3 arsenate respiratory reductase (ARR), the key enzyme involved in this metabolism

    Malasarn et al. biochemically characterize ARR as the arsenate respiratory reductase for ANA-3 arsenate respiration.

Provenance

Identifier source
TraitMech local identifier
Definition source
DOI:10.1073/pnas.1834303100

Parent traits (1)

Synonyms (2)

  • As(V) respiration EXACT_SYNONYM · DOI:10.1073/pnas.1834303100
  • respiratory As(V) reduction RELATED_SYNONYM · DOI:10.1073/pnas.1834303100

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Canonical examples (1)

Organisms cited as exemplars of this trait. Taxon ids are NCBITaxon and link out to the NCBI record.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for organism-level arsenate respiration before adding a TraitRecord xref.

CURATION TODO OPEN arsenate-respiration-xref-gap · raised by codex · 2026-09-14

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

The pinned METPO snapshot contains obsolete arsenate reduction and arsenate-reducing classes but no active organism-level arsenate respiration class. Potential GO, Rhea, EC, and protein-family terms for respiratory arsenate reductase are narrower than the whole-organism anaerobic respiration phenotype, and future groundings must keep ArrAB respiratory reduction separate from ArsC cytosolic detoxification.

Curation history

  1. · MINTED_TRAITMECH_ID · codex

    Minted arsenate respiration as a DOI-backed anaerobic respiration TraitRecord after a repository-wide duplicate review covering ignored and hidden files; the local METPO snapshot has only obsolete arsenate-reduction classes and the replacement placeholder is reserved in proposals/metpo_traitmech_v72.

  2. · TIGHTENED_CANONICAL_EXAMPLE · codex

    Tightened the ANA-3 canonical example note to the DOI-backed isolation and facultative arsenate-respiration evidence without making a broader genetic-tractability claim.