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flagellar arrangement

traitmech:000056 · CLASS · REVIEWED

A morphology trait describing the number and spatial distribution of flagella on a cell (the flagellation pattern), e.g. monotrichous, lophotrichous, amphitrichous, or peritrichous.

Flagellar arrangement set by FlhF/FlhG flagellation pattern

Evidence-backed causal sketch linking FlhF/FlhG-regulated flagellar placement to the cellular flagellation pattern.

Flagellar arrangement set by FlhF/FlhG flagellation pattern Interactive directed graph showing evidence-backed causal relationships for flagellar arrangement.

Edge evidence

  • bacterial-type flagellum defines flagellar arrangement METPO:2007500

    The cellular distribution of flagella defines the arrangement.

    • DOI:10.3390/biom9070279 Bacterial flagellum review supports the flagellum as the locomotory organelle whose number and placement define the arrangement.
  • FlhF/FlhG flagellar placement regulation regulates flagellar arrangement RO:0002211

    FlhF/FlhG set the species-specific flagellation pattern.

    • DOI:10.1093/femsre/fuv034 Schuhmacher et al. describe FlhF/FlhG governance of the flagellation pattern.
  • FlhG stimulates GTPase activity of FlhF

    FlhG stimulates the GTPase activity of FlhF, a conserved core regulatory interaction governing flagellar placement.

    • DOI:10.1038/s41467-024-50274-4 Dornes 2024: "FlhG acts on FlhF by stimulating its GTPase activity" - conserved core regulatory edge.
  • FlhF directs to cell pole FliF (MS-ring protein)

    FlhF is required to direct the initial MS-ring protein FliF to the cell pole, nucleating basal-body assembly.

    • DOI:10.1038/s41467-024-50274-4 Dornes 2024: "FlhF... is required to direct the initial MS-ring protein FliF to the cell pole."
  • FlhF binds FliG

    FlhF binds FliG, coupling the placement regulator to C-ring/MS-ring assembly.

    • DOI:10.1038/s41467-024-50274-4 Dornes 2024: FlhF B-domain (FliG Interaction Domain) is necessary and sufficient for FliG binding.
  • FliG engages / recruits FliF (MS-ring protein)

    FlhF-bound FliG engages the MS-ring protein FliF, recruiting a FliF-FliG complex to the pole.

    • DOI:10.1038/s41467-024-50274-4 Dornes 2024: "FlhF-bound FliG then engages the MS-ring protein FliF, recruiting a FliF-FliG complex to the pole."
  • FlhF establishes marking of future flagellar assembly site

    FlhF marks the future flagellar assembly site, after which basal-body assembly proceeds.

    • DOI:10.1093/femsre/fuv034 Schuhmacher 2015: "After FlhF marked the future flagellar site, assembly of the basal body will proceed."
  • marking of future flagellar assembly site occurs at cell pole

    The marking of the future flagellar assembly site localizes basal-body building blocks to the cell pole.

    • DOI:10.1093/femsre/fuv034 Schuhmacher 2015: FlhF B-domain recruits MS-ring component FliF to the cell pole.

Provenance

Source
METPO (2025-11-25)
Definition source
DOI:10.1093/femsre/fuv034

Parent traits (1)

Children (4)

Synonyms (1)

  • flagellation pattern RELATED_SYNONYM · DOI:10.1093/femsre/fuv034

kg-microbe context

Matched 1 kg-microbe node via parent_proxy.

  • METPO:1000704 [-2.371, -2.707, -4.290, +4.186, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · PROPOSED_FROM_RESEARCH · claude

    Proposed candidate MORPHOLOGY axis class (flagellar arrangement) under the existing flagellated class (METPO:1000704); parent of monotrichous/lophotrichous/ amphitrichous/peritrichous.

  2. · CURATED_CAUSAL_GRAPH · claude

    Added evidence-backed causal graph (FlhF/FlhG flagellation pattern) with GO node grounding and RO/METPO predicate groundings; promoted PROPOSED to REVIEWED.

  3. · ENRICH_CAUSAL_GRAPH · claude

    Added 6 evidence-backed generic edges (6 new nodes) from the deep-research report.

  4. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0060187×1).

  5. · GROUND_CAUSAL_NODES · claude

    Grounded 3 causal-node grounding field(s) via mappings/node_grounding.tsv (UniProtKB:A0A656AC42×1, UniProtKB:Q2N2M1×1, UniProtKB:A0A016XEK1×1).