KNOWN HISTORICAL DUF
Families
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373 of 8,296 families. Page 6 of 8.
| Pfam | Family | Seed status | Characterization | Evidence counts | Proteins | Structures | AlphaFold | Other Mechs | Curation status |
|---|---|---|---|---|---|---|---|---|---|
| PF09964 | Uncharacterized protein conserved in bacteria (DUF2198) DUF2198 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 550 | 0 | 353 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF10016 | Predicted secreted protein (DUF2259) DUF2259 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 529 | 0 | 325 | ProteinTraitsMech trait record | SEEDED |
| PF10805 | Phage Mu-like releasin family DUF2730 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 528 | 0 | 370 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF10020 | Uncharacterized protein conserved in bacteria (DUF2262) DUF2262 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 524 | 0 | 327 | ProteinTraitsMech trait record | SEEDED |
| PF19587 | Uncharacterised methyltransferase family (DUF6094) DUF6094 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 522 | 0 | 303 | ProteinTraitsMech trait record | SEEDED |
| PF19601 | Bacterial PH-like domain (DUF6106) DUF6106 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 512 | 0 | 361 | ProteinTraitsMech trait record | SEEDED |
| PF10060 | Uncharacterized membrane protein (DUF2298) DUF2298 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 509 | 0 | 388 | ProteinTraitsMech trait record | SEEDED |
| PF09988 | Uncharacterized metal-binding protein (DUF2227) DUF2227 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 462 | 0 | 283 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF02680 | Uncharacterized ArCR, COG1888 DUF211 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 452 | 3 | 404 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF06806 | Putative excisionase (DUF1233) DUF1233 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 450 | 1 | 263 | ProteinTraitsMech: 4; ProteinTraitsMech trait record | SEEDED |
| PF03761 | Nematode trypsin-6-like family DUF316 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 445 | 0 | 430 | ProteinTraitsMech trait record | SEEDED |
| PF09999 | Uncharacterized protein conserved in archaea (DUF2240) DUF2240 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 435 | 0 | 406 | ProteinTraitsMech trait record | SEEDED |
| PF09918 | Uncharacterized protein containing a ferredoxin domain (DUF2148) DUF2148 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 427 | 0 | 346 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF11223 | SPP41, DUF3020 DUF3020 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 427 | 0 | 293 | ProteinTraitsMech: 2; ProteinTraitsMech trait record | SEEDED |
| PF10097 | Predicted membrane protein (DUF2335) DUF2335 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 421 | 0 | 267 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF09843 | Predicted membrane protein (DUF2070) DUF2070 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 407 | 0 | 386 | ProteinTraitsMech trait record | SEEDED |
| PF10045 | Uncharacterized conserved protein (DUF2280) DUF2280 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 388 | 0 | 197 | ProteinTraitsMech trait record | SEEDED |
| PF09960 | Uncharacterised protein conserved in bacteria (DUF2194) DUF2194 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 387 | 1 | 203 | ProteinTraitsMech trait record | SEEDED |
| PF09920 | Uncharacterized protein conserved in archaea (DUF2150) DUF2150 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 386 | 0 | 359 | ProteinTraitsMech trait record | SEEDED |
| PF25853 | DUF6311 C-terminal domain DUF6311_C |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 386 | 0 | 234 | ProteinTraitsMech trait record | SEEDED |
| PF20784 | DUF5575 C-terminal domain DUF5575_C |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 368 | 0 | 251 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF09883 | DUF2110 central domain DUF2110 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 363 | 0 | 348 | ProteinTraitsMech trait record | SEEDED |
| PF24872 | DUF2110 N-terminal domain DUF2110_N |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 363 | 0 | 349 | ProteinTraitsMech trait record | SEEDED |
| PF24873 | DUF2110 C-terminal domain DUF2110_C |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 363 | 0 | 348 | ProteinTraitsMech trait record | SEEDED |
| PF09947 | Uncharacterized protein conserved in archaea (DUF2180) DUF2180 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 362 | 0 | 234 | ProteinTraitsMech trait record | SEEDED |
| PF20783 | DUF5575 N-terminal domain DUF5575_N |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 343 | 0 | 261 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF30500 | DUF3084-associated C-terminal helical hairpin DUF3084_C |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 334 | 0 | 209 | ProteinTraitsMech trait record | SEEDED |
| PF17738 | DUF5575 central RNaseH like domain DUF5575 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 326 | 0 | 240 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF10078 | Uncharacterized protein conserved in bacteria (DUF2316) DUF2316 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 318 | 0 | 209 | ProteinTraitsMech trait record | SEEDED |
| PF22665 | DUF6293 C-terminal winged helix domain WHD_DUF6293 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 318 | 0 | 299 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF12426 | RNA dependent RNA polymerase DUF3674 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 315 | 15 | 50 | ProteinTraitsMech: 2; ProteinTraitsMech trait record | SEEDED |
| PF12990 | Domain of unknonw function from B. Theta Gene description (DUF3874) DUF3874 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 294 | 0 | 208 | ProteinTraitsMech trait record | SEEDED |
| PF10062 | Predicted secreted protein (DUF2300) DUF2300 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 288 | 0 | 149 | ProteinTraitsMech: 4; ProteinTraitsMech trait record | SEEDED |
| PF09909 | Uncharacterized protein conserved in bacteria (DUF2138) DUF2138 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 286 | 0 | 152 | ProteinTraitsMech: 2; ProteinTraitsMech trait record | SEEDED |
| PF20405 | DUF6695 C-terminal domain DUF6695 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 286 | 0 | 161 | ProteinTraitsMech trait record | SEEDED |
| PF18958 | Putative zinc dependent peptidase (DUF5700) DUF5700 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 268 | 0 | 185 | ProteinTraitsMech trait record | SEEDED |
| PF10004 | Uncharacterized protein conserved in bacteria (DUF2247) DUF2247 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 267 | 0 | 151 | ProteinTraitsMech trait record | SEEDED |
| PF26383 | DUF6079 second domain DUF6079_2nd |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 267 | 0 | 188 | ProteinTraitsMech trait record | SEEDED |
| PF10008 | Uncharacterized protein conserved in bacteria (DUF2251) DUF2251 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 265 | 0 | 166 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF26384 | DUF6079 third domain DUF6079_3rd |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 260 | 0 | 183 | ProteinTraitsMech trait record | SEEDED |
| PF15763 | Regulator of human erythroid cell expansion (RHEX) DUF4692 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 257 | 0 | 220 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF19468 | DUF6005 N-terminal domain DUF6005 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 255 | 0 | 147 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF30710 | DUF6005 C-terminal domain DUF6005_C |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 253 | 0 | 146 | ProteinTraitsMech trait record | SEEDED |
| PF04507 | Csa1 family DUF576 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 248 | 4 | 198 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF09888 | Uncharacterized protein conserved in archaea (DUF2115) DUF2115 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 248 | 0 | 212 | ProteinTraitsMech: 2; ProteinTraitsMech trait record | SEEDED |
| PF09839 | DUF2066 DUF2066 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 247 | 0 | 141 | ProteinTraitsMech trait record | SEEDED |
| PF10726 | Protein of function (DUF2518) DUF2518 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 245 | 0 | 148 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF08735 | Putative pyruvate format-lyase activating enzyme (DUF1786) DUF1786 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 240 | 0 | 207 | ProteinTraitsMech trait record | SEEDED |
| PF12461 | Spiroplasma phage ORF1-like family DUF3688 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 237 | 0 | 201 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF04473 | Transglutaminase-like domain DUF553 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 232 | 0 | 184 | ProteinTraitsMech: 5; ProteinTraitsMech trait record | SEEDED |
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