KNOWN HISTORICAL DUF
Families
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373 of 8,296 families. Page 1 of 8.
| Pfam | Family | Seed status | Characterization | Evidence counts | Proteins | Structures | AlphaFold | Other Mechs | Curation status |
|---|---|---|---|---|---|---|---|---|---|
| PF02698 | DUF218 domain DUF218 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 25,685 | 1 | 15,881 | ProteinTraitsMech: 7; ProteinTraitsMech trait record | SEEDED |
| PF14291 | ZMYM1/FAM200, RNase-like domain DUF4371 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 21,818 | 0 | 15,479 | ProteinTraitsMech: 5; ProteinTraitsMech trait record | SEEDED |
| PF13340 | Putative transposase of IS4/5 family (DUF4096) DUF4096 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 18,629 | 0 | 11,006 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF01784 | Duf34/NIF3 (NGG1p interacting factor 3) DUF34_NIF3 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 18,574 | 16 | 12,676 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF05598 | Transposase domain (DUF772) DUF772 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 17,572 | 0 | 11,560 | ProteinTraitsMech: 7; ProteinTraitsMech trait record | SEEDED |
| PF10035 | Uncharacterized protein conserved in bacteria (DUF2179) DUF2179 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 15,886 | 1 | 10,419 | ProteinTraitsMech: 8; ProteinTraitsMech trait record | SEEDED |
| PF12473 | Kinesin protein DUF3694 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 15,238 | 0 | 3,731 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF02622 | AlgH-like DUF179 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 14,657 | 8 | 9,886 | ProteinTraitsMech: 4; ProteinTraitsMech trait record | SEEDED |
| PF04239 | YetF C-terminal domain DUF421 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 14,102 | 1 | 8,907 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF14309 | LONGIFOLIA 1/2-like C-terminal domain DUF4378 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 12,694 | 0 | 9,735 | ProteinTraitsMech: 5; ProteinTraitsMech trait record | SEEDED |
| PF08044 | DUF1707 SHOCT-like domain DUF1707 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 12,418 | 0 | 7,035 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF04379 | ApaG domain DUF525 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 11,744 | 9 | 8,600 | ProteinTraitsMech: 10; ProteinTraitsMech trait record | SEEDED |
| PF01935 | Helicase HerA, central domain DUF87 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 11,479 | 38 | 7,658 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF10988 | Putative auto-transporter adhesin, head GIN domain DUF2807 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 10,865 | 14 | 7,045 | ProteinTraitsMech trait record | SEEDED |
| PF02582 | RMND1/Sif2-Sif3/Mrx10, DUF155 DUF155 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 9,028 | 0 | 7,471 | ProteinTraitsMech: 2; ProteinTraitsMech trait record | SEEDED |
| PF09990 | Predicted membrane protein (DUF2231) DUF2231 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 8,774 | 0 | 5,434 | ProteinTraitsMech trait record | SEEDED |
| PF14383 | DUF761-associated sequence motif VARLMGL |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 8,540 | 0 | 6,836 | ProteinTraitsMech trait record | SEEDED |
| PF02643 | Uncharacterized ACR, COG1430 DUF192 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 8,199 | 2 | 5,508 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF03445 | Putative nucleotidyltransferase DUF294 DUF294 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 8,040 | 0 | 5,051 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF02639 | Uncharacterized BCR, YaiI/YqxD family COG1671 DUF188 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 8,028 | 0 | 5,272 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF09917 | Uncharacterized protein conserved in bacteria (DUF2147) DUF2147 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 7,871 | 1 | 5,177 | ProteinTraitsMech trait record | SEEDED |
| PF06465 | CHD subfamily II, DUF1087 DUF1087 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 7,326 | 2 | 432 | ProteinTraitsMech: 8; ProteinTraitsMech trait record | SEEDED |
| PF10009 | Uncharacterized protein conserved in bacteria (DUF2252) DUF2252 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 7,123 | 0 | 4,039 | ProteinTraitsMech trait record | SEEDED |
| PF09365 | Conserved hypothetical protein (DUF2461) DUF2461 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 7,048 | 0 | 4,670 | ProteinTraitsMech trait record | SEEDED |
| PF09413 | Putative prokaryotic signal transducing protein DUF2007 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 6,871 | 1 | 4,539 | ProteinTraitsMech trait record | SEEDED |
| PF09835 | Uncharacterized protein conserved in bacteria (DUF2062) DUF2062 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 6,840 | 0 | 4,660 | ProteinTraitsMech trait record | SEEDED |
| PF10067 | Predicted membrane protein (DUF2306) DUF2306 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 6,637 | 0 | 4,300 | ProteinTraitsMech trait record | SEEDED |
| PF08551 | Eukaryotic integral membrane protein (DUF1751) DUF1751 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 6,596 | 0 | 5,575 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF11938 | TLR4 regulator and MIR-interacting MSAP DUF3456 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 6,340 | 1 | 5,514 | ProteinTraitsMech: 5; ProteinTraitsMech trait record | SEEDED |
| PF01940 | Integral membrane protein DUF92 DUF92 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 6,136 | 0 | 4,924 | ProteinTraitsMech: 7; ProteinTraitsMech trait record | SEEDED |
| PF22752 | Inactive DUF488-N3 subclade DUF488-N3i |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,812 | 0 | 3,595 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF09837 | Uncharacterized protein conserved in bacteria (DUF2064) DUF2064 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,624 | 1 | 3,623 | ProteinTraitsMech trait record | SEEDED |
| PF09997 | Predicted membrane protein (DUF2238) DUF2238 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,616 | 0 | 3,777 | ProteinTraitsMech: 2; ProteinTraitsMech trait record | SEEDED |
| PF02681 | Divergent PAP2 family DUF212 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,597 | 0 | 4,122 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF10011 | Predicted membrane protein (DUF2254) DUF2254 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,235 | 0 | 3,287 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF17761 | DUF1016 N-terminal domain DUF1016_N |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,224 | 0 | 3,460 | ProteinTraitsMech: 4; ProteinTraitsMech trait record | SEEDED |
| PF12419 | SNF2 Helicase protein DUF3670 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,188 | 0 | 2,794 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF19029 | DUF883 C-terminal glycine zipper region DUF883_C |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,187 | 0 | 3,297 | ProteinTraitsMech: 6; ProteinTraitsMech trait record | SEEDED |
| PF07364 | Metallopeptidase family M81 DUF1485 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,172 | 2 | 3,251 | ProteinTraitsMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF10025 | Uncharacterized conserved protein (DUF2267) DUF2267 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 5,059 | 1 | 2,920 | ProteinTraitsMech trait record | SEEDED |
| PF06469 | Neurobeachin-like, DUF1088 DUF1088 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,966 | 0 | 517 | ProteinTraitsMech: 5; ProteinTraitsMech trait record | SEEDED |
| PF03990 | G5-linked-Ubiquitin-like domain DUF348 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,937 | 1 | 3,055 | ProteinTraitsMech: 8; TraitMech: 1; ProteinTraitsMech trait record | SEEDED |
| PF16087 | Helix-turn-helix domain (DUF4817) DUF4817 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,912 | 0 | 3,904 | ProteinTraitsMech trait record | SEEDED |
| PF16313 | Met-zincin DUF4953 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,879 | 0 | 3,081 | ProteinTraitsMech trait record | SEEDED |
| PF05346 | Eukaryotic membrane protein family DUF747 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,804 | 0 | 4,083 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF13584 | BatD DUF11 like domain BatD |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,713 | 0 | 3,016 | ProteinTraitsMech trait record | SEEDED |
| PF09832 | Uncharacterized protein conserved in bacteria (DUF2059) DUF2059 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,656 | 3 | 2,967 | ProteinTraitsMech trait record | SEEDED |
| PF10350 | THADA/TRM732, DUF2428 DUF2428 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,556 | 1 | 662 | ProteinTraitsMech: 7; ProteinTraitsMech trait record | SEEDED |
| PF09844 | Uncharacterized conserved protein (COG2071) DUF2071 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,522 | 0 | 2,825 | ProteinTraitsMech: 3; ProteinTraitsMech trait record | SEEDED |
| PF12609 | Wound-induced protein DUF3774 |
KNOWN HISTORICAL DUF | UNSCORED | Not scored | 4,377 | 0 | 3,517 | ProteinTraitsMech trait record | SEEDED |
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