cell length small

Edge evidence

• standard growth conditions enables adder size control RO:0002327

  Standard nutrient/temperature regimes maintain adder size control.

  • DOI:10.1016/j.cell.2014.11.022 cells grow by a fixed amount between divisions Supports adder control under typical growth regimes.
• adder size control produces cell length small METPO:2000202

  Adder homeostasis under standard conditions yields a narrow length distribution in the small range.

  • DOI:10.1016/j.cell.2014.11.022 cells grow by a fixed amount between divisions Supports small length as a typical adder-controlled outcome.
• cell length small is a cell length rdfs:subClassOf

  Small cell length is a quantitative bin of the cell-length phenotype.

  • DOI:10.1016/j.cub.2014.07.022 cell size is tightly controlled Supports small length as a value within the regulated cell-length distribution.
• FtsZ abundance rate_limiting_for cell division timing

  FtsZ levels are a rate-limiting factor for division timing; higher FtsZ promotes earlier division.

  • DOI:10.1038/s41467-024-54242-w FtsZ numbers are identified as one of the rate-limiting factors for cell divisions.
• FtsZ ring formation modulates cell length RO:0002211

  Delayed FtsZ ring formation delays division until the cell reaches a larger size, increasing cell length.

  • DOI:10.1038/s41467-023-41487-0 Delay cell division until the cell reaches a larger size.
• FtsN activates FtsWI septal PG synthase complex RO:0002213

  FtsN allosterically activates the FtsWI septal PG synthase complex.

  • DOI:10.1038/s41467-024-52217-5 Activation of the sPG synthase (FtsWI within the FtsQLBWI complex) depends on FtsN.
• septal peptidoglycan synthesis promotes Z-ring condensation and stability RO:0002213

  Septal peptidoglycan synthesis feeds back to promote Z-ring condensation and stability.

  • DOI:10.1038/s41467-024-52217-5 Septal cell wall synthesis feeds back to promote Z ring condensation and stability.
• FtsZ proto-ring (with FtsA/ZipA) organizes divisome assembly

  The FtsZ proto-ring with FtsA/ZipA organizes divisome assembly and is required for localization of other divisome proteins.

  • DOI:10.1038/s41579-023-00942-x FtsZ is required for localization of all other divisome proteins.
• Min system and nucleoid occlusion positions FtsZ positioning at midcell

  Min system and nucleoid occlusion position FtsZ at midcell for proper division-site placement.

  • DOI:10.1038/s42003-024-07279-y For positioning FtsZ at mid cell division sites.