cell length

Edge evidence

• elongation rate contributes to cell length RO:0002326

  Elongation rate sets how rapidly a cell extends along its long axis between divisions.

  • DOI:10.1016/j.cub.2014.07.022 cell size is tightly controlled Supports growth/elongation rate as a determinant of cell size.
• adder size control regulates cell length RO:0002211

  Adder size control sets the inter-division length increment that determines average cell length.

  • DOI:10.1016/j.cell.2014.11.022 cells grow by a fixed amount between divisions Supports the adder principle as the size-control rule producing the length distribution.
• FtsZ ring (divisome) assembles at division-site placement

  FtsZ assembles at the future division site to initiate cytokinesis.

  • DOI:10.1038/nrmicro2671 FtsZ ring at the future division site Supports FtsZ-ring assembly as the proximate divisome event.
• division-site placement causes cytokinesis biolink:causes

  Division-site placement directs constriction and cytokinesis.

  • DOI:10.1038/nrmicro2671 directs cell division Supports division-site placement as the trigger for cytokinesis.
• cytokinesis resets cell length

  Cytokinesis halves the mother cell, resetting daughter cell length.

  • DOI:10.1016/j.cell.2014.11.022 cells grow by a fixed amount between divisions Supports division as the event that resets length each generation.
• Rod complex (elongasome) mediates sidewall peptidoglycan synthesis

  The Rod complex/elongasome drives sidewall peptidoglycan synthesis.

  • DOI:10.3389/fcimb.2023.1205488 elongasome drives sidewall peptidoglycan synthesis necessary for rod shape and lengthening of the cell prior to division.
• sidewall peptidoglycan synthesis contributes to cell length RO:0002326

  Sidewall PG synthesis lengthens the cell prior to division.

  • DOI:10.3389/fcimb.2023.1205488 sidewall peptidoglycan synthesis necessary for the lengthening of the cell prior to division.
• Rod complex (elongasome) mediates elongation rate

  The Rod complex/elongasome mediates cell elongation.

  • DOI:10.1038/s42003-024-07279-y elongation is mediated by the Rod complex (the elongasome).
• FtsA and ZipA (proto-ring tethers) attaches FtsZ ring (divisome)

  FtsA and ZipA tether FtsZ to the membrane forming the proto-ring.

  • DOI:10.1038/s41579-023-00942-x FtsZ membrane attachment depends on tethers FtsA and ZipA (the proto-ring).
• FtsWI septal PG synthase drives septum synthesis

  FtsWI septal PG synthases drive septum synthesis.

  • DOI:10.1038/s41579-023-00942-x essential septal peptidoglycan synthases FtsW and FtsI (FtsWI) that drive septum synthesis.
• septum synthesis contributes to cytokinesis RO:0002326

  Septum synthesis drives division constriction completing cytokinesis.

  • DOI:10.1038/s41579-023-00942-x inactivation of essential divisome proteins blocks division, altering cell length; septum synthesis drives division constriction.
• Min system and nucleoid occlusion regulates division-site placement RO:0002211

  Min system and nucleoid occlusion determine division site placement via localized negative regulation of FtsZ polymerization.

  • DOI:10.1038/s41579-023-00942-x the Min system and nucleoid occlusion act as localized negative regulators of FtsZ polymerization and thus determine division site placement.