alpha-fucosidase activity

traitmech:000152 · CLASS · PROPOSED

A physiological enzyme-activity phenotype in which a cell produces active alpha-fucosidase enzymes that hydrolyze alpha-L-fucosides to L-fucose and an alcohol.

Trait evidence (2)

https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/51.html
Reaction: an α-L-fucoside + H2O = L-fucose + an alcohol

The NC-IUBMB EC 3.2.1.51 entry defines alpha-L-fucosidase by its accepted name and hydrolytic reaction, grounding the enzyme activity named by the organism-level phenotype.
DOI:10.1128/jcm.22.3.333-335.1985
Positive reactions for alpha-glucosidase, beta-glucosidase, alpha-fucosidase, and alpha-glucuronidase suggest that "B. forsythus" may be saccharolytic.

Tanner et al. detected alpha-fucosidase in the then-proposed oral species Bacteroides forsythus with the API ZYM enzyme activity panel.

Provenance

Identifier source: TraitMech local identifier
Definition source: https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/51.html

Parent traits (1)

phenotype METPO:1000059

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Canonical examples (1)

Organisms cited as exemplars of this trait. Taxon ids are NCBITaxon and link out to the NCBI record.

Tannerella forsythia NCBITaxon:28112 DOI:10.1128/jcm.22.3.333-335.1985 Tanner et al. reported alpha-fucosidase-positive reactions for "Bacteroides forsythus", the basonym of Tannerella forsythia, in API ZYM profiles.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for alpha-fucosidase activity before adding a TraitRecord xref.

CURATION TODO OPEN alpha-fucosidase-activity-xref-gap · raised by codex · 2026-09-12

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

GO:0004560 carries the alpha-L-fucosidase activity label but denotes the enzyme molecular function rather than the organism-level alpha-fucosidase production phenotype, so it is appropriate as a causal-node grounding rather than an equivalent TraitRecord xref.

Curation history

2026-09-12T01:09:57Z · MINTED_TRAITMECH_ID · codex
Minted alpha-fucosidase activity as a URL/DOI-backed TraitRecord after a repository-wide duplicate review covering ignored and hidden files; METPO has no exact alpha-fucosidase activity class yet.