alpha-galactosidase activity

traitmech:000149 · CLASS · PROPOSED

A physiological enzyme-activity phenotype in which a cell produces active alpha-galactosidase enzymes that hydrolyze alpha-1,6-linked galactose residues in oligosaccharides and polymeric galactomannans.

Trait evidence (2)

DOI:10.3109/07388551.2013.794124
The enzyme α-galactosidase (α-D-galactoside galactohydrolase; EC 3.2.1.22) catalyzes the hydrolysis of α-1,6-linked galactose residues in oligosaccharides and polymeric galactomannan.

Katrolia et al. define alpha-galactosidase as EC 3.2.1.22, an enzyme that hydrolyzes alpha-1,6-linked galactose residues, grounding the enzyme activity named by the organism-level phenotype.
DOI:10.1128/jcm.22.3.333-335.1985
Selenomonas sputigena was positive for α-galactosidase, β-galactosidase, and α-glucosidase (API ZYM strip) and for α-glucosidase, β-glucosidase, and α-galactosidase (API An-Ident strip).

Tanner et al. detected alpha-galactosidase in Selenomonas sputigena with the API ZYM enzyme activity panel and the API An-Ident strip.

Provenance

Identifier source: TraitMech local identifier
Definition source: DOI:10.3109/07388551.2013.794124

Parent traits (1)

phenotype METPO:1000059

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Canonical examples (1)

Organisms cited as exemplars of this trait. Taxon ids are NCBITaxon and link out to the NCBI record.

Selenomonas sputigena NCBITaxon:69823 DOI:10.1128/jcm.22.3.333-335.1985 Tanner et al. reported Selenomonas sputigena as positive for alpha-galactosidase in API ZYM and API An-Ident enzyme activity panels.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for alpha-galactosidase activity before adding a TraitRecord xref.

CURATION TODO OPEN alpha-galactosidase-activity-xref-gap · raised by codex · 2026-09-11

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

GO:0004557 denotes the alpha-galactosidase/melibiase molecular function rather than the organism-level alpha-galactosidase production phenotype, so it is appropriate as a causal-node grounding rather than an equivalent TraitRecord xref.

Curation history

2026-09-11T23:46:20Z · MINTED_TRAITMECH_ID · codex
Minted alpha-galactosidase activity as a DOI-backed TraitRecord after a repository-wide duplicate review covering ignored and hidden files; METPO has no exact alpha-galactosidase activity class yet.