beta-glucuronidase activity

traitmech:000151 · CLASS · PROPOSED

A physiological enzyme-activity phenotype in which a cell produces active beta-glucuronidase enzymes that hydrolyze beta-D-glucuronosides to D-glucuronate and an alcohol.

Trait evidence (2)

https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/31.html
Reaction: a β-D-glucuronoside + H2O = D-glucuronate + an alcohol

The NC-IUBMB EC 3.2.1.31 entry defines beta-glucuronidase by its accepted name and hydrolytic reaction, grounding the enzyme activity named by the organism-level phenotype.
DOI:10.1128/aem.50.6.1383-1387.1985
The beta-glucuronidase produced by E. coli cleaves the MUG substrate to yield a fluorescent end product.

Moberg used beta-glucuronidase cleavage of MUG to detect Escherichia coli in food samples.

Provenance

Identifier source: TraitMech local identifier
Definition source: https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/31.html

Parent traits (1)

phenotype METPO:1000059

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Canonical examples (1)

Organisms cited as exemplars of this trait. Taxon ids are NCBITaxon and link out to the NCBI record.

Escherichia coli NCBITaxon:562 DOI:10.1128/aem.50.6.1383-1387.1985 Moberg reported beta-glucuronidase-mediated cleavage of MUG by Escherichia coli in a fluorogenic detection assay.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for beta-glucuronidase activity before adding a TraitRecord xref.

CURATION TODO OPEN beta-glucuronidase-activity-xref-gap · raised by codex · 2026-09-12

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

GO:0004566 carries the same beta-glucuronidase activity label but denotes the enzyme molecular function rather than the organism-level beta-glucuronidase production phenotype, so it is appropriate as a causal-node grounding rather than an equivalent TraitRecord xref.

Curation history

2026-09-12T00:37:27Z · MINTED_TRAITMECH_ID · codex
Minted beta-glucuronidase activity as a URL/DOI-backed TraitRecord after a repository-wide duplicate review covering ignored and hidden files; METPO has no exact beta-glucuronidase activity class yet.
2026-09-12T00:55:15Z · FIX_EVIDENCE_SNIPPET · codex
Corrected the IUBMB EC 3.2.1.31 water token from HTML-derived H_{2}O to source-visible H2O after Claude Code Review flagged the snippet as non-verbatim in https://github.com/CultureBotAI/TraitMech/issues/807.