beta-N-acetylhexosaminidase activity

traitmech:000157 · CLASS · PROPOSED

A physiological enzyme-activity phenotype in which a cell produces active beta-N-acetylhexosaminidase enzymes that hydrolyze terminal, non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

Trait evidence (2)

https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/52.html
Reaction: Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-β-D-hexosaminides

The NC-IUBMB EC 3.2.1.52 entry defines beta-N-acetylhexosaminidase by its accepted reaction, grounding the glycosidase activity named by the organism-level phenotype.
DOI:10.1021/jf020965x
Serratia marcescens YS-1, a chitin-degrading microorganism, produced mainly N-acetylhexosaminidase

Kurakake et al. reported production of N-acetylhexosaminidase by Serratia marcescens YS-1, supporting this as a bacterial beta-N-acetylhexosaminidase activity phenotype.

Provenance

Identifier source: TraitMech local identifier
Definition source: https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/52.html

Parent traits (1)

phenotype METPO:1000059

Synonyms (4)

beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity EXACT_SYNONYM · https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/52.html
N-acetylhexosaminidase RELATED_SYNONYM · DOI:10.1021/jf020965x
beta-N-acetylglucosaminidase RELATED_SYNONYM · https://iubmb.qmul.ac.uk/enzyme/EC3/2/1/52.html
N-acetyl-beta-glucosaminidase RELATED_SYNONYM · TraitMech#453

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Canonical examples (1)

Organisms cited as exemplars of this trait. Taxon ids are NCBITaxon and link out to the NCBI record.

Serratia marcescens NCBITaxon:615 DOI:10.1021/jf020965x Kurakake et al. reported Serratia marcescens YS-1 as mainly producing N-acetylhexosaminidase.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for beta-N-acetylhexosaminidase activity before adding a TraitRecord xref.

CURATION TODO OPEN beta-n-acetylhexosaminidase-activity-xref-gap · raised by codex · 2026-09-12

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

GO:0004563 denotes beta-N-acetylhexosaminidase molecular function rather than the organism-level beta-N-acetylhexosaminidase production phenotype, so it is appropriate as a causal-node grounding rather than an equivalent TraitRecord xref.

Curation history

2026-09-12T04:12:07Z · MINTED_TRAITMECH_ID · codex
Minted beta-N-acetylhexosaminidase activity as a URL/DOI-backed TraitRecord after a repository-wide duplicate review covering ignored and hidden files; METPO has no exact beta-N-acetylhexosaminidase activity class yet.