TraitMech

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carboxylesterase activity

traitmech:000156 · CLASS · PROPOSED

A physiological enzyme-activity phenotype in which a cell produces active carboxylesterase enzymes that hydrolyze carboxylic esters to alcohols and carboxylates.

Trait evidence (2)

  • https://iubmb.qmul.ac.uk/enzyme/EC3/1/1/1.html
    Reaction: A carboxylic ester + H_{2}O = an alcohol + a carboxylate

    The NC-IUBMB EC 3.1.1.1 entry defines carboxylesterase by its accepted reaction, grounding the ester-hydrolase activity named by the organism-level carboxylesterase phenotype.

  • DOI:10.1128/JCM.43.8.3713-3717.2005
    Alkaline phosphatase, esterase (C4), esterase lipase (C8), leucine arylamidase, acid phosphatase, and naphthol-AS-BI-phosphohydrolase were clearly positive

    Otsuka et al. detected clear esterase (C4) and esterase lipase (C8) API ZYM reactions in the five Corynebacterium resistens isolates they characterized, supporting this as a directly assayed bacterial carboxylesterase activity phenotype.

Provenance

Identifier source
TraitMech local identifier
Definition source
https://iubmb.qmul.ac.uk/enzyme/EC3/1/1/1.html

Parent traits (1)

Synonyms (1)

  • carboxylic-ester hydrolase activity EXACT_SYNONYM · https://iubmb.qmul.ac.uk/enzyme/EC3/1/1/1.html

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Canonical examples (1)

Organisms cited as exemplars of this trait. Taxon ids are NCBITaxon and link out to the NCBI record.

Discussions and Knowledge Gaps (1)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Resolve an exact external ontology class for carboxylesterase activity before adding a TraitRecord xref.

CURATION TODO OPEN carboxylesterase-activity-xref-gap · raised by codex · 2026-09-12

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

GO:0106435 denotes carboxylesterase molecular function rather than the organism-level carboxylesterase production phenotype, so it is appropriate as a causal-node grounding rather than an equivalent TraitRecord xref.

Curation history

  1. · MINTED_TRAITMECH_ID · codex

    Minted carboxylesterase activity as a URL/DOI-backed TraitRecord after a repository-wide duplicate review covering ignored and hidden files; METPO has no exact carboxylesterase activity class yet.