parasexuality

Trait evidence (3)

• DOI:10.1093/emboj/cdg235

  Thus, an efficient parasexual cycle can be performed in C.albicans, one that leads to the reassortment of genetic material in this organism.

  Bennett and Johnson (2003), PMID:12743044. The snippet is an exact span of the directly retrieved Europe PMC abstract. Main-text experiments and Figures 1-9 were inspected in the author-hosted PDF: https://static1.squarespace.com/static/56463117e4b0770d2cd2d163/t/564e4d55e4b04412d33a3036/1447972181154/the%2Bembo%2Bjournal%2B2003%2Bbennett.pdf. Marked CAI4-derived Candida albicans strains formed tetraploid mating products; chromosome loss yielded diploid or near-diploid progeny that could mate again. Flow cytometry and multiple marker/MTL readouts support ploidy reduction; marker loss alone can also arise by recombination. The cycle need not reach haploidy. The paper leaves conventional meiosis possible under untested conditions. Its supplementary media, mating and PCR details remain unread, and its unpublished meiotic-gene deletion observations are not used as mechanistic proof.

• DOI:10.1128/ec.00128-13

  The diploid products are themselves mating competent, thereby establishing a parasexual cycle in this species for the first time.

  Seervai et al. (2013), PMID:24123269. The snippet exact-matches the directly retrieved Europe PMC abstract. Publisher Methods, Results, Discussion and strain tables were read, and Figures 3 and 4 were visually inspected. Marked Candida tropicalis tetraploids produced near-diploid progeny on sorbose; remating, MTL genotyping and DNA-content measurements support a repeatable cycle. 2-DOG resistance selects GAL1 loss, not necessarily chromosome loss. The Figure 4 caption's wild-type wording does not erase the CAY2060 arg4/arg4 tester genotype reported in Table 1 and Methods. The response to presporulation medium differs from C. albicans. The supplementary Figure S1 caption and labels were read as PDF text, but the actual supplemental plot was not visually inspected. No natural canonical example is inferred from these marker-strain experiments.

• DOI:10.1038/s41467-019-12376-2

  These results indicate that C. albicans CCL represents a 'parameiosis' that blurs the conventional boundaries between mitosis and meiosis.

  Anderson et al. (2019), PMID:31558727. The snippet is an exact span of the directly retrieved Europe PMC abstract. Publisher Introduction and Results were read, but full Methods, actual figures and supplements were not inspected. Concerted chromosome loss (CCL) in C. albicans includes high inter-homolog recombination and functions of Spo11 and Rec8. Their effects on chromosome stability and recombination are different endpoints: loss of SPO11 increases marker loss while reducing recombination, whereas loss of REC8 reduces both in the tested CCL assays. Absence of conventional meiosis does not mean absence of meiosis-associated proteins. Neither homologue presence alone nor these assays establish a conventional meiotic cycle. Protein identities, native strain provenance and assay-specific causal edges remain uncurated.