reversible nematode-paralyzing activity

traitmech:000722 · CLASS · PROPOSED

A physiological capability of a microorganism to induce a loss of active nematode movement that reverses after exposure to the microorganism or its products ends.

Trait evidence (2)

https://journals.flvc.org/nematropica/article/view/64427
Bioassays revealed that filtrates of P. lilacinus and Paecilomyces marquandii caused reversible paralysis of male and juvenile R. similis.

Kilama et al. 2007, English Abstract, printed page 215/PDF page 1. Direct publisher HTML/PDF and typeset match; native verifier skips URL references, not VERIFIED. Needle-probed immobilization at 2 h was followed by rinsing and reassessment labelled 21 h; Discussion says 21 h after rinsing. Bioassay 2 lacks recovery testing; bioassay 3 has a high-paralysis pH control and bioassay 5 is null against controls. Actual Figure 1 measures initial paralysis; Results/Table 2 address recovery. Repeated counts are not individual trajectories. No universal host/stage response or dose threshold is inferred.
https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_5/pt5/nemato/27861.pdf
Secondly, the majority of larvae are able to recover the mobility in fresh water following all treatment times up to 48 h.

Cayrol, Djian and Pijarowski 1989, Results, Study of the reversibility of the toxic effect, printed page 335/PDF page 5; actual Figure 3 inspected. This recovery result concerns M. arenaria larvae exposed to Brazilian P. lilacinus culture filtrate: 10-day motionless, aerated, illuminated malt culture, 15 g/L, undiluted filtrate, varied exposure, then 24 h in water. Needle probing and water/pH-matched medium controls are described. Summary says less than 48 h, Results through 48 h; no universal threshold is adopted. Typeset all is quoted; PDF text extraction misreads it as dl. Native URL verification is skipped. This is recovery support, not a standalone producer-identity excerpt or proof of a neural mechanism.

Provenance

Identifier source: TraitMech local identifier
Definition source: https://journals.flvc.org/nematropica/article/view/64427

Parent traits (1)

phenotype METPO:1000059

kg-microbe context

No kg-microbe node embedding matched this record in the 2026-04-25 deepwalk.

Discussions and Knowledge Gaps (2)

Open questions attached to this trait. Seeded by just knowledge-gap-scan and curated; see the corpus-wide index.

Refine the hierarchy without losing the microbial actor and recovery requirement.

CURATION TODO OPEN reversible-nematode-paralysis-scope-and-hierarchy · raised by codex · 2026-10-14

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

This is the microorganism's capability, not its own nonmotility or the nematode's susceptibility. Recovery after removal is required; immobility, reduced speed, reduced egg hatch, population suppression, trapping or attraction alone is insufficient. The same producer or product may kill under other conditions; no organism-level disjointness follows. Phenotype METPO:1000059 is the conservative parent. Lethal activity, fungal nematophagy, trap formation and attraction are related, not necessary parents. No exact active or deprecated METPO counterpart was identified in the documented pinned/current screen; v598 proposes the class. Nematostatic terminology, chemical roles and sequence annotations are not exact synonyms or xrefs. Infection, feeding and a particular molecular mechanism are not required.

Resolve source discrepancies and strain provenance before adding taxa or mechanisms.

KNOWLEDGE GAP OPEN reversible-nematode-paralysis-source-and-mechanism-limits · raised by codex · 2026-10-14

Not yet attached to a section of this record — a curator sets attaches_to (e.g. causal_graphs#some_edge) so the gap shows beside the mechanism it concerns.

Kilama assigns 22R5-2 to both species in Methods, versus lilacinus 22R5-1/marquandii 22R5-2 in Results/Figure 1 and marquandii 22R5-1 in Discussion. It also varies 11N4-8/11N8-4 and 23N5-2/23N-5. Upper dose is 375 in Methods/Results but 325 in Table 2; lower dose is 125 in Methods/Table 2 but 150 in Results, in microliters/mL. These discrepancies are not silently corrected. Cayrol's proposed neurotropic action is unresolved, not a demonstrated target. No common active chemical, protein, causal graph, canonical taxon, field efficacy or environmental safety is asserted. Taxonomic authority and strain provenance remain unchecked for exemplar purposes. Source hashes, bounded notice checks, URL-verifier skips and inspection limits are retained in the verification sidecar. No full raw-data or statistical reanalysis was performed.

Curation history

2026-10-14T01:02:02Z · MINTED_TRAITMECH_ID · codex
Added a microbial reversible nematode-paralyzing capability with two stable-URL primary studies and typeset-verified snippets. Retained recovery criteria, assay/control and source discrepancies; native URL references are skipped, not VERIFIED. Reserved 000722, v598 and 1067500-1067599 after ignored/hidden current-copy, retained history and open/draft PR checks with numeric false positives adjudicated. No exact active METPO counterpart identified in the inspected scope. Other records unchanged. Timestamp records observed acceptance after assessment, not the later file write.

Recorded curation sessions

2026-10-14T01:05:22Z · codex
- CREATE — Add reversible nematode-paralyzing activity
  Added one PROPOSED microorganism-level capability requiring movement recovery after exposure ends. Two stable-URL primary studies carry 19-word and 22-word directly inspected excerpts. Kilama supplies definition authority; Cayrol independently supports recovery, not standalone producer identity. The native verifier skips URL references; manual HTML/PDF and typeset checks are distinct from native VERIFIED. Retained control, strain, dose, timing and text-extraction discrepancies in evidence notes and two OPEN discussions. No canonical taxa, exact synonyms, xrefs, proteins or graph asserted. Ignored/hidden current-copy, retained-history and open/draft PR reservation checks found no exact record or competing allocation after numeric false-positive adjudication. Initial Git regex control failure was corrected before completed historical checks. v598 reserves 1067500-1067599 for local 000722. Timestamp in the trait records observed acceptance; this history records the later CREATE. Other records and protected spore germination are unchanged.
Read this curation session