NaCl optimum mid1

Edge evidence

• seawater-like NaCl engages modest osmoadaptation

  Seawater-like NaCl engages a moderate osmoadaptive program.

  • DOI:10.1093/femsre/fuy009 slight halophile Supports seawater-range NaCl as the context for slight-halophile optima.
• modest osmoadaptation produces NaCl optimum mid1 METPO:2000202

  A modest osmoadaptive program yields a 1–3% NaCl-optimum setpoint.

  • DOI:10.1093/femsre/fuy009 slight halophile Supports the 1–3% optimum as the slight-halophile outcome.
• NaCl optimum mid1 is a NaCl optimum rdfs:subClassOf

  NaCl optimum mid1 is a quantitative bin of the NaCl-optimum phenotype.

  • DOI:10.1093/femsre/fuy009 optimal NaCl Supports the 1–3% optimum as a value within the NaCl-optimum distribution.
• NaCl optimum mid1 defines slight halophile / halotolerant physiology METPO:2007500

  A 1-3% (w/v) NaCl optimum defines slight-halophile/halotolerant physiology.

  • DOI:10.3390/biotech14020049 "slight halophiles (0.2-0.5 M or 1-3% NaCl)" - supports trait scope/boundary.
• slight halophile / halotolerant physiology associated with salt-in osmoregulation strategy biolink:associated_with

  Slight-halophile physiology is broadly associated with the salt-in (K+ accumulation) strategy.

  • DOI:10.3389/frmbi.2023.1329925 "The salt-in strategy involves maintaining a high intracellular concentration of inorganic salts, mainly potassium" - general mechanism across halotolerant/halophilic microbes.
• slight halophile / halotolerant physiology associated with compatible-solute osmoregulation strategy biolink:associated_with

  Slight-halophile physiology is broadly associated with the compatible-solute (salt-out) strategy.

  • DOI:10.3389/frmbi.2023.1329925 "The salt-out strategy relies on biosynthesis or uptake of compatible solutes" - general osmoadaptation mechanism.
• elevated external NaCl induces accumulation of glycine betaine

  Rising external NaCl increases intracellular glycine betaine.

  • DOI:10.1128/aem.00145-24 "The intracellular content of compatible solutes, including glycine betaine, glutamate, and proline, increases with rising salinity levels" - directional relationship is broadly applicable.
• elevated external NaCl induces accumulation of L-proline

  Rising external NaCl increases intracellular L-proline.

  • DOI:10.1128/aem.00145-24 "The intracellular content of compatible solutes, including glycine betaine, glutamate, and proline, increases with rising salinity levels" - proline is a general osmolyte.