temperature delta mid2
METPO:1000486 · CLASS · REVIEWED
A temperature delta phenotype with a growth-supporting temperature breadth of approximately 20–30 °C, characteristic of organisms with broad thermal-tolerance breadth.
Temperature-delta-mid2 broad-breadth thermal adaptation
Edge evidence
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broad thermal-adaptation flexibility
produces
temperature delta mid2
METPO:2000202Broad thermal-adaptation flexibility yields a 20–30 °C temperature-delta breadth.
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DOI:10.1146/annurev-micro-091313-103612more unsaturated fatty acids
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temperature delta mid2
is a
temperature delta
rdfs:subClassOfTemperature delta mid2 is a quantitative bin of the temperature-delta phenotype.
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DOI:10.1016/s0300-9629(97)00003-0adapted to environments of high temperature
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acyl-lipid desaturase (Des)
increases abundance of
unsaturated fatty acids
Desaturase remodels existing lipids, raising unsaturated:saturated fatty acid ratio.
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DOI:10.1128/spectrum.03925-23
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unsaturated fatty acids
increases
membrane fluidity / homeoviscous adaptation
RO:0002213Unsaturation fluidizes the membrane, supporting homeoviscous adaptation.
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DOI:10.1128/spectrum.03925-23
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membrane fluidity / homeoviscous adaptation
enables
broad thermal-adaptation flexibility
RO:0002327Maintaining membrane fluidity across temperatures underpins broad thermal-adaptation flexibility.
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DOI:10.1128/spectrum.03925-23
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RpoS sigma factor (sigma-S)
positively regulates expression of
otsAB trehalose biosynthesis operon
RpoS controls cold-shock-triggered induction of the otsAB operon.
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DOI:10.1007/s12275-023-00031-x
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otsAB trehalose biosynthesis operon
produces
trehalose
METPO:2000202The otsAB pathway synthesizes trehalose.
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DOI:10.1007/s12275-023-00031-x
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trehalose
contributes to
cold / cold-shock tolerance
RO:0002326Trehalose acts as a compatible solute supporting cold-shock tolerance.
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DOI:10.1007/s12275-023-00031-x
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Provenance
- Source
- METPO (2025-11-25)
- Definition source
- DOI:10.1146/annurev-micro-091313-103612
Parent traits (1)
Synonyms (1)
- Td_20_30
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1000486[-3.073, +0.032, -2.627, +2.668, …]
Nearest neighbors in embedding space
- environment pH range mid2 0.802
- environment pH range low 0.794
- environment temperature range low 0.785
- environment pH range mid1 0.780
- environment temperature range mid1 0.765
- environment pH range mid3 0.760
- environment temperature range very low 0.742
- environment pH optimum mid1 0.718
Curation history
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·
SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_CAUSAL_GRAPH · claude
Added DOI-backed definition and causal graph linking broad thermal-adaptation flexibility to the temperature-delta-mid2 bin.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1, rdfs:subClassOf×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 6 evidence-backed generic edges (7 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 4 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002213×1, RO:0002327×1, METPO:2000202×1, RO:0002326×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:27208×1).