crescent shaped

Edge evidence

• crescentin localizes to inner cell curvature biolink:located_in

  Crescentin localizes along the inner curvature of the cell.

  • DOI:10.1038/emboj.2009.61 localizes to the inner cell curvature Supports crescentin as an inner-curvature-localized shape protein.
• crescentin regulates peptidoglycan growth bias RO:0002211

  Crescentin mechanically constrains cell-wall growth to create differential curvature.

  • DOI:10.1038/emboj.2009.61 mechanical control of cell growth Supports a mechanical growth-control role for crescentin.
• peptidoglycan growth bias generates crescent cell curvature biolink:produces

  Biased peptidoglycan growth or strain generates curved geometry.

  • DOI:10.1038/emboj.2009.61 bacterial cell curvature through mechanical control Supports differential growth mechanics as a curvature mechanism.
• crescent cell curvature produces crescent shaped METPO:2000202

  Curved cell-body geometry produces the crescent-shaped trait.

  • DOI:10.1016/S0092-8674(03)00935-8 required for the ... shapes of Caulobacter Supports crescentin-dependent curved morphology as the trait endpoint.
• crescentin decreases rate of peptidoglycan insertion at inner curvature

  Crescentin reduces peptidoglycan insertion on the side where it is located, setting up a growth-rate gradient.

  • DOI:10.1038/emboj.2009.61 the crescentin structure would not only reduce peptidoglycan insertion at the side where crescentin is located but would also generate a gradient of increasing peptidoglycan growth rates
• peptidoglycan insertion at inner curvature contributes to differential peptidoglycan insertion rates RO:0002326

  Reduced inner-side insertion creates a gradient of differential peptidoglycan insertion rates around the circumference.

  • DOI:10.1038/emboj.2009.61 would also generate a gradient of increasing peptidoglycan growth rates
• differential peptidoglycan insertion rates produces crescent shaped METPO:2000202

  Differential peptidoglycan insertion rates around the cell circumference produce cell curvature.

  • DOI:10.1038/emboj.2009.61 the crescentin structure caused differential peptidoglycan insertion rates around the cell circumference to produce cell curvature
• crescentin envelope association required for crescent shaped

  Association of crescentin with the cell envelope is required to produce curvature; attachment-defective mutants fail to curve.

  • DOI:10.1128/jb.01371-09 Envelope association is required for crescentin function (attachment-defective mutants fail to produce curvature)