spore forming

Edge evidence

• forespore develops into resistant endospore biolink:develops_into

  The forespore compartment matures into a resistant endospore.

  • DOI:10.1146/annurev.genet.30.1.297 within which a spore is produced Supports forespore development into the spore.
• spore cortex contributes to resistant endospore RO:0002326

  Cortex synthesis contributes to endospore structure and resistance.

  • DOI:10.1038/nrmicro2921 spore surface layers Supports specialized spore layers as functional components of the endospore.
• spore coat protects resistant endospore

  The multilayered coat protects and structures the endospore surface.

  • DOI:10.1038/nrmicro2921 assembly and functions of the multilayered coat Supports the spore coat as a protective assembly.
• dipicolinic acid contributes to resistant endospore RO:0002326

  Dipicolinic acid contributes to spore resistance and stability.

  • DOI:10.1111/j.1365-2672.2005.02736.x mechanisms are responsible for the resistance of spores Supports chemical and structural factors in Bacillus spore resistance.
• resistant endospore manifests as spore forming METPO:2007400

  Production of resistant endospores manifests the spore-forming trait.

  • DOI:10.1038/nrmicro2921 production of a highly resistant dormant cell type known as the spore Supports the trait endpoint.
• SpoIID required for forespore engulfment

  SpoIID is required for forespore engulfment.

  • DOI:10.3390/microbiolres14020035 Genes spoIID, spoIIM, spoIIP are required for engulfment.
• SpoIIM required for forespore engulfment

  SpoIIM is required for forespore engulfment.

  • DOI:10.3390/microbiolres14020035 Genes spoIID, spoIIM, spoIIP are required for engulfment.
• SpoIIP required for forespore engulfment

  SpoIIP is required for forespore engulfment.

  • DOI:10.3390/microbiolres14020035 Genes spoIID, spoIIM, spoIIP are required for engulfment.
• cortex synthesis contributes to resistant endospore RO:0002326

  Cortex synthesis after engulfment contributes to mature spore formation.

  • DOI:10.3390/microbiolres14020035 Cortex synthesis within the intermembrane space and coat assembly follow engulfment.
• spore coat assembly contributes to spore core protection and dormancy RO:0002326

  Spore coat assembly contributes to core protection, dehydration, and dormancy.

  • DOI:10.3390/microbiolres14020035 Coat proteins influence core protection, spore-core dehydration and dormancy.
• Spo0E-family phosphatases negatively regulates phosphorylated Spo0A (Spo0A~P)

  Spo0E-family phosphatases dephosphorylate and inhibit Spo0A~P.

  • DOI:10.3390/microbiolres14020035 A second negative control is provided by Spo0E-family Spo0A-specific phosphatases.