motile

Edge evidence

• metabolic energy generates ion motive force biolink:produces

  Metabolism supports ion gradients that can power motility.

  • DOI:10.3389/fmicb.2021.659464 ion motive force powering the bacterial flagellar motor Supports energy transduction from ion gradients into motor function.
• ion motive force enables flagellar motor RO:0002327

  Ion motive force powers rotation of the flagellar motor.

  • DOI:10.3389/fmicb.2021.659464 The Dynamic Ion Motive Force Powering Review directly addresses ion motive force powering flagellar motors.
• flagellar motor enables motile RO:0002327

  Flagellar rotation enables independent bacterial movement.

  • DOI:10.3390/biom9070279 responsible for motility Supports flagella-driven motility.
• type IV pilus enables motile RO:0002327

  Type IV pilus extension and retraction enable surface motility.

  • DOI:10.1038/s41579-019-0195-4 enable T4P to perform Supports pilus-mediated twitching and related motility functions.
• chemotaxis signaling directs motile RO:0002211

  Chemotaxis signaling regulates motility direction in response to environmental changes.

  • DOI:10.3390/biom9070279 migrate towards more desirable environments Supports chemotaxis regulation of motile behavior.
• MotA-MotB stator complex acts as transmembrane H+ channel activity

  The MotA-MotB stator acts as a transmembrane H+ channel.

  • DOI:10.3390/biom14121488 it can act as a transmembrane H+ channel
• transmembrane H+ channel activity generates flagellar motor torque biolink:produces

  H+ flux through the stator generates torque via electrostatic interaction with FliG.

  • DOI:10.3390/biom14121488 conducts H+ through the channel to generate torque by electrostatic interactions between MotA and FliG
• flagellar motor torque acts on FliG rotor protein

  Torque is generated by electrostatic interaction between the stator and the FliG rotor.

  • DOI:10.3390/biom14121488 electrostatic interactions between MotA and FliG generate torque on the rotor
• flagellar motor torque enables flagellar motor RO:0002327

  Torque generation drives rotation of the flagellar motor.

  • DOI:10.3390/biom14121488 a membrane-embedded rotary motor fueled by an ion motive force across the cytoplasmic membrane
• CheA histidine kinase phosphorylates CheY response regulator

  Phosphorylated CheA transfers phosphate to the response regulator CheY.

  • DOI:10.3390/biom14121488 Phosphorylated CheA transfers its phosphate group to a response regulator called CheY
• CheY response regulator binds flagellar C-ring switch complex

  Phosphorylated CheY binds the C-ring switch complex to control rotation direction.

  • DOI:10.3390/biom14121488 Phosphorylated CheY (CheY-P) binds to the C-ring
• flagellar C-ring switch complex regulates chemotaxis signaling RO:0002211

  CheY-P binding to the C-ring switches motor rotation direction, implementing chemotactic responses.

  • DOI:10.3390/biom14121488 allowing the motor to switch the direction of rotation from CCW to CW
• PilB extension ATPase promotes type IV pilus extension RO:0002213

  PilB ATPase powers type IV pilus extension/assembly.

  • DOI:10.1128/msphere.00390-24 PilB (extension ATPase)
• PilT retraction ATPase promotes type IV pilus retraction RO:0002213

  PilT ATPase powers type IV pilus retraction/disassembly.

  • DOI:10.1128/msphere.00390-24 PilT (retraction ATPase)
• type IV pilus extension enables twitching motility RO:0002327

  Cycles of T4P extension and retraction power twitching surface motility.

  • DOI:10.1128/msphere.00390-24 recurrent cycles of T4P assembly (extension) and disassembly (retraction) power surface movement
• type IV pilus retraction enables twitching motility RO:0002327

  Cycles of T4P extension and retraction power twitching surface motility.

  • DOI:10.1128/msphere.00390-24 recurrent cycles of T4P assembly (extension) and disassembly (retraction) power surface movement
• twitching motility enables motile RO:0002327

  Twitching motility is a form of independent surface movement.

  • DOI:10.1128/msphere.00390-24 recurrent cycles of T4P assembly and disassembly power surface movement (twitching motility)
• SprB adhesin surface movement drives gliding motility

  Movement of the SprB adhesin along the outer membrane drives gliding motility.

  • DOI:10.1128/jb.00068-24 gliding... is driven by the surface movement of adhesins (notably SprB) along the outer membrane
• gliding motility enables motile RO:0002327

  Gliding motility is a non-flagellar mechanism of independent movement.

  • DOI:10.1128/jb.00068-24 gliding is a form of surface motility driven by adhesin movement