halophilic

Edge evidence

• high-salt environment selects for halophilic METPO:2007401

  Halophilic microorganisms are adapted to growth in high-salt environments.

  • DOI:10.1093/femsre/fuy009 Hypersaline environments ... inhabited by halophilic Review supports hypersaline habitats as the environmental context for halophily.
• sodium chloride causes osmotic stress biolink:causes

  Elevated NaCl creates osmotic pressure that requires cellular adaptation.

  • DOI:10.1186/1746-1448-4-2 ways they cope with the high salt concentrations Review frames halophily around coping with high environmental salt.
• compatible solutes mitigates osmotic stress METPO:2007407

  Compatible solutes are one major osmoadaptation mechanism in halophilic microorganisms.

  • DOI:10.1093/femsre/fuy009 synthesize organic osmotic solutes Supports organic compatible-solute accumulation as an osmotic adaptation mechanism.
• salt-in strategy mitigates osmotic stress METPO:2007407

  Salt-in ion accumulation is an alternative osmoadaptation strategy.

  • DOI:10.1093/femsre/fuy009 KCl accumulating Halobacterium salinarum Supports intracellular KCl accumulation as a high-salt adaptation.
• compatible solutes contributes to halophilic RO:0002326

  Compatible-solute accumulation supports growth under high salinity.

  • DOI:10.1371/journal.pone.0168818 allows microorganisms to cope with high salinities Halomonas elongata study supports compatible solutes as a mechanism enabling halophilic growth.
• Na+/H+ antiporter expels sodium ion

  Sodium is excluded from the cytoplasm with the help of an Na+/H+ antiporter.

  • DOI:10.3390/microorganisms12081738 sodium is excluded from the cytoplasm with the help of an Na+/H+ antiporter
• K+ uniport system imports potassium ion METPO:2000208

  Potassium enters the cell through a uniport system during salt-in osmoadaptation.

  • DOI:10.3390/microorganisms12081738 Potassium enters the cell through a uniport system
• salt-in strategy associated with acidified proteome biolink:associated_with

  Organisms employing the salt-in strategy exhibit an acidified proteome.

  • DOI:10.3390/microorganisms12081738 microorganisms employing this strategy exhibit an acidified proteome
• sodium chloride induces oxidative stress

  NaCl shock induces oxidative stress in addition to osmotic stress.

  • DOI:10.1186/s12934-024-02358-5 NaCl shock induced two major stresses, namely osmotic stress and oxidative stress
• ectABC operon biosynthesizes ectoine

  The conserved ectABC operon performs de novo biosynthesis of ectoine.

  • DOI:10.1128/aem.00479-23 Biosynthesis of ectoine is de novo from L-aspartic acid, performed by the conserved operon ectABC
• L-aspartic acid is precursor of ectoine

  Ectoine is biosynthesized de novo from L-aspartic acid.

  • DOI:10.1128/aem.00479-23 Biosynthesis of ectoine is de novo from L-aspartic acid
• ectoine is a compatible solutes rdfs:subClassOf

  Ectoine is a major organic compatible solute used in osmoadaptation.

  • DOI:10.1128/aem.00479-23 Ectoine is a canonical compatible solute synthesized via the ectABC operon.