stenohaline

Edge evidence

• narrow salinity range defines stenohaline METPO:2007500

  Stenohaline microorganisms thrive within a narrow salinity range.

  • DOI:10.1186/s40168-024-01817-w narrow range of salinity Microbiome study explicitly defines stenohaline microorganisms by a narrow salinity range.
• salinity shift causes osmotic imbalance biolink:causes

  Salinity shifts create osmotic imbalance across the membrane.

  • DOI:10.1186/s40168-024-01817-w In response to osmotic imbalance Supports osmotic imbalance as a response to salinity change.
• osmotic imbalance regulates water flux across cytoplasmic membrane RO:0002211

  Osmotic imbalance drives water flux across the membrane.

  • DOI:10.1186/s40168-024-01817-w water immediately rushes into the cell Supports water flux during osmotic imbalance.
• salinity-adaptation genes regulates stenohaline RO:0002211

  Salinity adaptation gene repertoires help determine salinity niche breadth; limited repertoires can correspond to narrow tolerance.

  • DOI:10.1186/s40168-024-01817-w genes associated with microbial salinity adaptation The constraint direction is inferred from the study's salinity adaptation analysis; kept broad because organism-specific gene sets vary.
• salinity shift exceeds tolerance of stenohaline

  Large salinity changes can exceed the narrow tolerance range of stenohaline organisms.

  • DOI:10.1186/s40168-024-01817-w Organisms thriving within a narrow range of salinity Supports the ecological interpretation that large salinity excursions exceed stenohaline niche breadth.
• cyclic di-AMP inhibits K+ import systems RO:0002212

  c-di-AMP binds RCK-type gating subunits to inhibit potassium influx.

  • DOI:10.1128/mmbr.00181-23 c-di-AMP binds RCK-type gating subunits inhibiting potassium influx; broad regulatory principle across c-di-AMP bacteria.
• cyclic di-AMP inhibits compatible-solute importer OpuA RO:0002212

  c-di-AMP binds CBS-containing compatible-solute importers and negatively regulates their transport.

  • DOI:10.1128/mmbr.00181-23 Binds CBS-containing compatible-solute importers (OpuA, OpuC, OpuD) and negatively regulates transport; general osmoadaptation regulation.
• low c-di-AMP state increases K+ and compatible-solute uptake RO:0002213

  Low c-di-AMP increases uptake of K+ and compatible solutes.

  • DOI:10.1128/mmbr.00181-23 Low c-di-AMP mutants show increased uptake of K+ and compatible solutes; broad bacterial principle.
• osmotic upshift triggers rapid K+ import

  Osmotic upshift triggers rapid K+ import as an early osmoadaptation response.

  • DOI:10.1093/femsml/uqad020 Many bacteria mount a rapid K+ import upon osmotic upshift; canonical osmoadaptation edge, not specific to stenohaline microbes.
• compatible-solute accumulation supports salt-out osmoadaptation

  Accumulation of compatible solutes supports the salt-out osmoadaptation strategy.

  • DOI:10.1093/femsml/uqad020 Longer-term strategy is salt-out via synthesis/import of compatible solutes (proline, ectoine, trehalose); general mechanistic edge.
• aquaporin water-channel activity enables facilitated water diffusion RO:0002327

  Aquaporin water-channel activity enables facilitated diffusion of water.

  • DOI:10.1186/s40168-024-01817-w COG0580 linked to GO:0015250 and described as enabling facilitated diffusion of water; functional edge.