chemoautolithotrophic
METPO:1000634 · CLASS · REVIEWED
A trophic type in which an organism uses chemical oxidation of inorganic compounds as the energy source and carbon dioxide as the primary carbon source for biosynthesis.
Chemoautolithotrophic inorganic energy and CO2 fixation
Edge evidence
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chemoautolithotrophic
uses electron donor
inorganic electron donor
METPO:2000009Chemoautolithotrophy uses inorganic chemical electron donors for energy.
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DOI:10.1016/B978-0-12-378630-2.00219-Xoxidize inorganic atoms or molecules
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ammonia
example of
inorganic electron donor
rdfs:subClassOfAmmonia is an inorganic donor in chemolithoautotrophic nitrification.
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DOI:10.1146/annurev.micro.55.1.485Chemolitho-autotrophic ammonia-oxidizing bacteria
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ferrous iron
example of
inorganic electron donor
rdfs:subClassOfFe(II) is a representative inorganic electron donor.
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DOI:10.1038/s41598-021-81412-3Fe(II) as the energy source
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inorganic electron donor
feeds electrons into
respiratory chain
METPO:2007402Inorganic donor oxidation feeds respiratory energy conservation.
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DOI:10.1016/j.bbabio.2008.09.008membrane-bound electron transport chain
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respiratory chain
produces
ATP
METPO:2000202Respiratory energy conservation produces ATP.
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DOI:10.1016/j.bbabio.2008.09.008drives ATP synthesis
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chemoautolithotrophic
uses carbon source
carbon dioxide
METPO:2000006Chemoautolithotrophs use CO2 as the primary carbon source.
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DOI:10.1128/AEM.02473-10autotrophic CO2 fixation
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carbon dioxide
fixed by
CO2-fixation pathway
METPO:2007404CO2 is fixed into cellular carbon by autotrophic pathways.
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DOI:10.1128/AEM.02473-10autotrophic carbon dioxide assimilation pathway
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CO2-fixation pathway
produces
biomass
METPO:2000202Fixed carbon supports biomass production.
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DOI:10.1038/nrmicro.2016.130microbial autotrophic production
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chemoautolithotrophic
requires
CO2-fixation pathway
Chemoautolithotrophy requires CO2 fixation to convert inorganic carbon into organic carbon.
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DOI:10.1186/s40168-023-01712-w
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chemoautolithotrophic
requires
oxidation of reduced inorganic compounds
Chemoautolithotrophy requires oxidation of reduced inorganic compounds for energy.
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DOI:10.1186/s40168-023-01712-w
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oxidation of reduced inorganic compounds
feeds electrons into
respiratory chain
METPO:2007402Oxidation of reduced inorganic compounds donates electrons to the respiratory chain.
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DOI:10.1186/s40168-023-01712-w
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chemoautolithotrophic
distinct from
chemo-organoheterotrophy
Chemolithoautotrophy (inorganic energy, CO2 carbon) is metabolically distinct from chemo-organoheterotrophy (organic energy and carbon).
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DOI:10.3390/molecules29102293
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Provenance
- Source
- METPO (2025-11-25)
- Author
- Luke Wang
- Definition source
- DOI:10.1016/B978-0-12-378630-2.00219-X
Parent traits (1)
Synonyms (1)
- chemoautolithotroph
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1000634[-0.916, -0.754, -3.630, +1.094, …]
Nearest neighbors in embedding space
- physiology trophic type 0.679
- physiology lithoautotrophic 0.658
- physiology hydrogenotrophic 0.656
- physiology photolithoautotrophic 0.654
- physiology photoorganoheterotrophic 0.639
- physiology carboxydotrophic 0.633
- physiology lithoheterotrophic 0.632
- physiology photolithotrophic 0.606
Curation history
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SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_CAUSAL_GRAPH · Codex
Added DOI-backed chemoautolithotrophy graph for inorganic electron donors, respiratory ATP generation, CO2 fixation, and biomass.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 4 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×2, METPO:2000009×1, METPO:2000006×1).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (rdfs:subClassOf×2).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007402×1, METPO:2007404×1).
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GROUND_CAUSAL_NODES · claude
Grounded 2 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:29033×1, GO:0022904×1).
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GROUND_CAUSAL_NODES · claude
Grounded 2 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007502×1, METPO:1007501×1).
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RETYPE_CAUSAL_NODES · claude
Re-typed 1 causal-node node_type field(s) to align with CausalNodeTypeEnum semantics: biomass: BIOLOGICAL_PROCESS → CHEMICAL ×1.
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0015977×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 4 evidence-backed generic edges (2 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007402×1).