hydrogenotrophic

Edge evidence

• hydrogenotrophic uses electron donor molecular hydrogen METPO:2000009

  Hydrogenotrophy uses molecular hydrogen as an electron donor.

  • DOI:10.21775/cimb.006.159 oxidation of hydrogen gas Supports H2 oxidation as a microbial energy process.
• hydrogenase oxidizes molecular hydrogen METPO:2000016

  Hydrogenases catalyze H2 oxidation.

  • DOI:10.21775/cimb.006.159 reversible oxidation of hydrogen gas Supports hydrogenase-catalyzed H2 oxidation.
• molecular hydrogen oxidized to protons and electrons METPO:2007405

  H2 oxidation yields protons and electrons.

  • DOI:10.21775/cimb.006.159 H2 <--> 2 H+ + 2 e- Supports the H2 redox half reaction.
• hydrogenase interacts with electron transport system biolink:interacts_with

  Hydrogenases can couple H2 metabolism to membrane electron transport systems.

  • DOI:10.21775/cimb.006.159 interact with membrane-bound electron transport systems Supports coupling to electron transport.
• electron transport system generates proton motive force biolink:produces

  Membrane-linked H2 metabolism can conserve energy as proton motive force.

  • DOI:10.21775/cimb.006.159 generation of a protonmotive force Supports membrane-linked energy conservation.
• carbon dioxide fixed by autotrophic CO2 fixation METPO:2007404

  CO2 supplies carbon for autotrophic hydrogenotrophic growth.

  • DOI:10.1128/AEM.02473-10 assimilation of CO2 Supports CO2 assimilation into cellular carbon.
• autotrophic CO2 fixation produces cellular carbon METPO:2000202

  Carbon fixation converts CO2 into cell carbon.

  • DOI:10.1128/AEM.02473-10 CO2 ... into cellular carbon Supports the carbon-assimilation output.
• H2 oxidation generates proton motive force biolink:produces

  Splitting H2 yields electrons and protons that can generate a proton gradient.

  • DOI:10.2138/gselements.16.1.39 Splitting H2 yields electrons and protons that can generate proton gradients and ATP; general mechanistic process-level edge.
• H2 oxidation coupled to reduction of carbon dioxide

  Hydrogen uptake can be coupled to reduction of CO2 in hydrogenotrophy.

  • DOI:10.3390/microorganisms7020053 The hydrogenase reaction is involved in coupling hydrogen uptake to the reduction of electron acceptors (e.g., nitrate, sulfate, and carbon dioxide).
• H2 oxidation coupled to reduction of oxygen

  H2 oxidation can be coupled to reduction of O2 (aerobic hydrogen oxidation).

  • DOI:10.2138/gselements.16.1.39 Hydrogen oxidation can be coupled to reduction of CO2/HCO3-, sulfate, nitrate, ferric iron and O2; high-confidence generic edge.
• H2 oxidation coupled to reduction of nitrate

  H2 oxidation can be coupled to reduction of nitrate in anaerobic respiration.

  • DOI:10.2138/gselements.16.1.39 Hydrogen oxidation can be coupled to reduction of CO2/HCO3-, sulfate, nitrate, ferric iron and O2; generic respiratory coupling edge.
• H2 oxidation coupled to reduction of sulfate

  H2 oxidation can be coupled to reduction of sulfate in anaerobic respiration.

  • DOI:10.2138/gselements.16.1.39 Hydrogen oxidation can be coupled to reduction of CO2/HCO3-, sulfate, nitrate, ferric iron and O2; generic respiratory coupling edge.
• H2 oxidation can support autotrophic CO2 fixation

  Coupling H2 oxidation to carbon fixation enables hydrogenotrophic chemosynthesis.

  • DOI:10.1111/1751-7915.14300 By coupling hydrogen oxidation to carbon fixation, hydrogenotrophic chemosynthesis is a viable energy generation strategy; trait-level edge.
• oxygen sensitivity constrains hydrogenase

  Differential O2 sensitivity across hydrogenase classes constrains their distribution and use.

  • DOI:10.2138/gselements.16.1.39 Hydrogenase classes show different sensitivity to O2 and diverse H2 affinities; broad environmental constraint across classes.