NaCl delta high

Edge evidence

• maximal osmoadaptive flexibility produces NaCl delta high METPO:2000202

  Maximal osmoadaptive flexibility yields an extreme NaCl-delta breadth.

  • DOI:10.1186/1746-1448-4-2 cope with the high salt concentrations Supports maximal osmoadaptive flexibility as the basis of extreme euryhalinity.
• NaCl delta high is a NaCl delta rdfs:subClassOf

  NaCl delta high is a quantitative bin of the NaCl-delta phenotype.

  • DOI:10.1093/femsre/fuy009 salinity range Supports >8% breadth as a value within the NaCl-delta distribution.
• high external salinity increases compatible-solute accumulation RO:0002213

  Rising external salinity increases intracellular compatible-solute content.

  • DOI:10.1128/aem.00145-24 Intracellular content of compatible solutes (glycine betaine, glutamate, proline) increases with rising salinity levels.
• intracellular K+ accumulation supports salt-in osmoadaptation

  Cytoplasmic K+ accumulation supports the salt-in osmoadaptation strategy.

  • DOI:10.1038/s41559-024-02505-6 Halophiles accumulate up to 4 M K+ in their cytoplasm as part of a salt-in strategy; concept-level edge across taxa.
• salt-in osmoadaptation associated with acidic proteome biolink:associated_with

  The salt-in strategy is associated with an acidic, low-pI proteome.

  • DOI:10.1038/s41559-024-02505-6 Proteome acidification is a hallmark of extreme halophily; median protein isoelectric points <=4.4.
• salinity transition across biomes drives proteome reorganization

  Salinity transitions across biomes drive proteome reorganization and pI shifts.

  • DOI:10.1126/sciadv.adg2059 Transitions accompanied by systematic changes in amino acid composition and isoelectric point distributions.
• hybrid salt-in/salt-out osmoregulation supports survival in fluctuating salinity environment

  Hybrid salt-in/salt-out osmoregulation supports survival across fluctuating salinity.

  • DOI:10.3389/frmbi.2023.1329925 MAGs contain genes for both the cheaper salt-in and more expensive salt-out strategies.
• hypersaline environment selects for halophilic osmoadaptation strategies METPO:2007401

  Hypersaline environments select for halophilic osmoadaptation strategies.

  • DOI:10.1038/s44185-024-00050-w Hypersaline environments containing >100-150 g/L salts; halophiles grow at >100-150 g/L.