NaCl delta low

Edge evidence

• limited osmoadaptive flexibility produces NaCl delta low METPO:2000202

  Limited osmoadaptive flexibility yields a narrow NaCl-delta breadth.

  • DOI:10.1093/femsre/fuy009 salinity range Supports limited osmoadaptive flexibility as the basis of stenohaline breadth.
• NaCl delta low is a NaCl delta rdfs:subClassOf

  NaCl delta low is a quantitative bin of the NaCl-delta phenotype.

  • DOI:10.1093/femsre/fuy009 salinity range Supports a narrow breadth as a value within the NaCl-delta distribution.
• ectoine biosynthesis capacity supports salt-tolerance breadth

  Ectoine biosynthesis capacity broadens NaCl tolerance; its loss narrows the growth range.

  • DOI:10.1128/aem.01905-23 Wild-type H. elongata synthesizes ectoine as a major osmolyte, whereas ectoine-deficient strains become salt sensitive; supports general role of ectoine pathway in broadening NaCl tolerance.
• compatible-solute transporters (Opu/ProU) supports limited osmoadaptive flexibility

  Salinity-induced Opu/ProU compatible-solute transporters underlie osmoadaptive flexibility; limited capacity contributes to narrow breadth.

  • DOI:10.1128/aem.00145-24 Proteomics showed salinity-linked increases in compatible-solute transporters (opuAC, proX/proV/proW) supporting osmoadaptation.
• TrkH potassium uptake system supports salt-tolerance breadth

  TrkH K+ uptake supports intracellular K+ homeostasis enabling salt tolerance; its absence may contribute to narrow breadth.

  • DOI:10.1128/aem.00145-24 TrkH listed among salinity-responsive proteins; simultaneous accumulation of compatible solutes and K+ supports salt adaptation.
• NhaC-family Na+/H+ antiporter supports salt-tolerance breadth

  NhaC Na+/H+ antiporters support ion homeostasis under salt stress; a candidate breadth-expanding mechanism whose absence may contribute to NaCl delta low.

  • DOI:10.1128/aem.00145-24 Proteomics show strong salinity-linked increases for NhaC-family antiporters (~3.27 and 3.22-fold).
• intracellular proline accumulation supports salt-tolerance breadth

  Increased intracellular proline as a compatible solute supports growth at higher NaCl, broadening tolerance.

  • DOI:10.1128/aem.01195-24 Engineered proline biosynthesis with blocked catabolism increased intracellular proline and restored growth at 8% NaCl; supports osmolyte role of proline in salt-tolerance breadth.
• salt-tolerance breadth is a NaCl delta rdfs:subClassOf

  Salt-tolerance breadth is the capacity quantified by the NaCl-delta phenotype.

  • DOI:10.1093/femsre/fuy009 Osmoadaptation review frames salinity tolerance breadth as the basis of the NaCl-delta (stenohaline vs euryhaline) distinction.