temperature delta mid1

METPO:1000485 · CLASS · REVIEWED

A temperature delta phenotype with a growth-supporting temperature breadth of approximately 10–20 °C, characteristic of organisms with moderate thermal-tolerance breadth.

Temperature-delta-mid1 moderate-breadth thermal adaptation

DOI-backed graph linking moderate thermal-adaptation flexibility to a 10–20 °C temperature growth breadth.

Temperature-delta-mid1 moderate-breadth thermal adaptation Interactive directed graph showing evidence-backed causal relationships for temperature delta mid1.

Edge evidence

  • moderate thermal-adaptation flexibility produces temperature delta mid1 METPO:2000202

    Moderate thermal-adaptation flexibility yields a 10–20 °C temperature-delta breadth.

    • DOI:10.1146/annurev-micro-091313-103612 more unsaturated fatty acids Supports moderate remodeling flexibility as the basis of an intermediate breadth.
  • temperature delta mid1 is a temperature delta rdfs:subClassOf

    Temperature delta mid1 is a quantitative bin of the temperature-delta phenotype.

    • DOI:10.1016/s0300-9629(97)00003-0 adapted to environments of high temperature Supports the 10–20 °C breadth as a value within the temperature-delta distribution.
  • decrease in ambient temperature increases cis-unsaturated fatty acid biosynthesis RO:0002213

    Colder temperature shifts fatty-acid synthesis toward cis-unsaturated products to preserve membrane function.

    • DOI:10.1007/s42770-023-01057-4 Ramon 2023 review: increased unsaturation (especially cis-MUFA) on temperature decrease; broad review support.
  • cis-unsaturated fatty acid biosynthesis increases membrane unsaturated fatty acids RO:0002213

    Cis-unsaturated fatty acid biosynthesis raises the unsaturated acyl-chain content of membrane lipids.

    • DOI:10.1007/s42770-023-01057-4 Ramon 2023: microbes increase cis-unsaturation to remodel membranes, a general cold-adaptation output.
  • membrane unsaturated fatty acids increases membrane fluidity RO:0002213

    More unsaturated acyl chains counteract cold-induced rigidification and restore membrane fluidity.

    • DOI:10.1128/spectrum.03925-23 Sidarta 2024: desaturation fluidizes membranes; central homeoviscous-adaptation edge, generalizable.
  • membrane physical-state change activates two-component cold signaling RO:0002213

    Cold-induced changes in the membrane liquid-crystalline state act as the upstream sensor activating two-component cold signaling.

    • DOI:10.1007/s42770-023-01057-4 Ramon 2023: cold sensing via changes in liquid-crystalline state of membranes that activate two-component signalling.
  • membrane fluidity enables moderate thermal-adaptation flexibility RO:0002327

    Maintained membrane fluidity across temperature shifts underlies the moderate thermal-adaptation flexibility that supports the breadth.

    • DOI:10.1128/spectrum.03925-23 Sidarta 2024: homeoviscous adaptation restores fluidity, the membrane-target of thermal adaptation.
  • Tmin and Tmax growth boundaries defines thermal niche / temperature breadth METPO:2007500

    Growth-supporting minimum and maximum temperatures flank the thermal function and mark the thermal niche/breadth.

    • DOI:10.3390/pr8010121 Noll 2020: Tmin and Tmax for growth flank the function and mark the thermal tolerance/niche of an organism.
  • thermal niche / temperature breadth is a temperature delta rdfs:subClassOf

    The Tmin/Tmax-bounded thermal niche is the breadth quantity captured by the temperature-delta phenotype.

    • DOI:10.3390/pr8010121 Noll 2020: thermal breadth treated as a cardinal-temperature bounded niche property.

Provenance

Source
METPO (2025-11-25)
Definition source
DOI:10.1146/annurev-micro-091313-103612

Synonyms (1)

  • Td_10_20 RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1000485 [+0.841, -0.698, +1.716, +3.076, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · CURATED_CAUSAL_GRAPH · claude

    Added DOI-backed definition and causal graph linking moderate thermal-adaptation flexibility to the temperature-delta-mid1 bin.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1, rdfs:subClassOf×1).

  4. · ENRICH_CAUSAL_GRAPH · claude

    Added 7 evidence-backed generic edges (8 new nodes) from the deep-research report.

  5. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 7 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002213×4, RO:0002327×1, METPO:2007500×1, rdfs:subClassOf×1).

  6. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007505×1).