carotenoid pigmentation
METPO:1003031 · CLASS · REVIEWED
A pigmentation phenotype caused by microbial production and accumulation of carotenoid pigments.
Carotenoid pigmentation crt-pathway mechanism
Edge evidence
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isoprenoid precursors
feed into
carotenoid biosynthesis
Isoprenoid precursors provide substrate for carotenoid production.
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DOI:10.1016/j.gene.2004.11.038isoprenoid precursor biosynthesis
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Crt enzymes
catalyzes
carotenoid biosynthesis
biolink:catalyzesCrt gene products catalyze bacterial carotenoid biosynthetic reactions.
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DOI:10.1080/1040841X.2025.2526423crt genes ... reactions they catalyze
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carotenoid biosynthesis
produces
conjugated carotenoids
METPO:2000202Carotenoid biosynthesis produces conjugated carotenoid pigments.
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DOI:10.1080/1040841X.2025.2526423biosynthesis pathways of bacterial carotenoids
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conjugated carotenoids
causes
yellow-orange-red color
biolink:causesConjugated carotenoids absorb visible light and produce yellow-orange-red pigmentation.
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DOI:10.1080/1040841X.2025.2526423red, pink, orange, and yellow pigmentation in bacteria
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yellow-orange-red color
manifests as
carotenoid pigmentation
METPO:2007400Yellow-orange-red visible color manifests carotenoid pigmentation.
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DOI:10.1080/1040841X.2025.2526423responsible for the red, pink, orange, and yellow pigmentation
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phytoene synthase
converts
phytoene
Phytoene synthase condenses prenyl diphosphate (GFDP) to form phytoene.
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DOI:10.3390/molecules29174235
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phytoene
is substrate for
phytoene desaturase
Phytoene is dehydrogenated by phytoene desaturase en route to lycopene.
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DOI:10.3390/molecules29174235
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phytoene desaturase
produces
lycopene
METPO:2000202Phytoene desaturase converts phytoene (via phytofluene) to lycopene.
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DOI:10.3390/molecules29174235
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lycopene cyclases
converts
cyclic carotenes
Lycopene cyclases cyclize lycopene into alpha-, epsilon-, and beta-carotene.
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DOI:10.3390/molecules29174235
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lycopene
is substrate for
lycopene cyclases
Lycopene is the substrate cyclized by lycopene cyclases.
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DOI:10.3390/molecules29174235
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cyclic carotenes
is a
conjugated carotenoids
rdfs:subClassOfCyclic carotenes are conjugated carotenoid pigments contributing to coloration.
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DOI:10.3390/molecules29174235
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Provenance
- Source
- METPO (2025-11-25)
- Definition source
- DOI:10.1080/1040841X.2025.2526423
Parent traits (1)
Synonyms (1)
- Pigment_carotenoid
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1003031[-2.345, -1.877, -1.987, -1.228, …]
Nearest neighbors in embedding space
- morphology pigmentation 0.913
- morphology green pigmented 0.818
- morphology red pigmented 0.800
- morphology black pigmented 0.795
- morphology pink pigmented 0.790
- morphology white pigmented 0.777
- morphology cream pigmented 0.772
- morphology brown pigmented 0.755
Curation history
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·
SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_WITH_LITERATURE · codex
Added DOI-backed definition and causal graph for isoprenoid precursors, Crt enzymes, carotenoid biosynthesis, conjugated carotenoids, and visible pigmentation.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1).
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·
GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:catalyzes×1, biolink:causes×1).
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·
GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007400×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0016117×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 6 evidence-backed generic edges (6 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1, rdfs:subClassOf×1).
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·
GROUND_CAUSAL_NODES · claude
Grounded 2 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:15948×1, CHEBI:35163×1).
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·
GROUND_CAUSAL_NODES · claude
Grounded 2 causal-node grounding field(s) via mappings/node_grounding.tsv (UniProtKB:A0A023WN98×1, UniProtKB:A0A060JDC8×1).