curved shaped

Edge evidence

• curvature scaffold localizes to inner cell curvature biolink:located_in

  Curvature scaffolds mark or constrain the inner curve of the cell.

  • DOI:10.1371/journal.pbio.1002565 scaffold-mediated delineation of an inner curvature Supports a common structural theme for curved and helical cells.
• curvature scaffold guides peptidoglycan growth pattern

  Curvature scaffolds bias wall growth or structural constraints along the inner curve.

  • DOI:10.1371/journal.pbio.1002565 guide PG synthesis Supports scaffold-guided peptidoglycan synthesis as a curvature mechanism in representative bacteria.
• peptidoglycan growth pattern generates cell-body curvature biolink:produces

  Spatially patterned wall growth or constraint generates cell-body curvature.

  • DOI:10.1016/j.cell.2016.12.019 asymmetrically patterns peptidoglycan insertion Vibrio evidence supports asymmetric PG insertion as one concrete route to curved rods.
• cell-body curvature produces curved shaped METPO:2000202

  Cell-body curvature produces the curved-shape trait.

  • DOI:10.1371/journal.pbio.1002565 vibrioid (curved) morphology Supports curved morphology as a recognized bacterial cell-shape class.
• MreB cytoskeletal guidance directs peptidoglycan growth pattern RO:0002211

  MreB localizes to specific curvature regions and directs localized cell-wall synthesis, supporting scaffold-guided PG remodeling.

  • DOI:10.3389/fmicb.2017.01264 the actin-like protein MreB localizes to specific curvature regions and directs localized cell-wall synthesis (broad mechanistic class).
• peptidoglycan growth pattern occurs via spatially constrained (zonal) peptidoglycan remodeling

  Because PG synthesis is constrained in space, all cell-wall growth and remodeling is "zonal", the route through which shape determinants act.

  • DOI:10.1371/journal.pbio.1002565 Because PG synthesis is constrained in space, all cell wall growth and remodeling can be described as "zonal" growth.
• curved shaped optimized for motility in viscous environments

  Curved/helical morphology appears optimized for motility, especially in viscous solutions (broad expert synthesis).

  • DOI:10.1371/journal.pbio.1002565 helical and curved cells appear to be optimized for motility, especially in viscous solutions.
• curved shaped promotes surface colonization, motility and virulence RO:0002213

  Curved and helical shapes are widespread among bacteria, promoting surface colonization, motility in viscous environments and virulence.

  • DOI:10.1038/s41467-024-51790-z curved and helical cell shapes ... are widespread among bacteria, promoting surface colonization, motility in viscous environments, and virulence.