ellipsoidal

Edge evidence

• PBP2b promotes peripheral peptidoglycan RO:0002213

  PBP2b promotes peripheral wall synthesis in ovococcal elongation.

  • DOI:10.1089/mdr.2014.0032 PBP2b of ovococci Supports PBP2b as part of the ovococcal elongation system.
• DivIVA regulates septal and peripheral peptidoglycan synthesis RO:0002211

  DivIVA regulates septal cleavage and peripheral peptidoglycan synthesis during ovococcal morphogenesis.

  • DOI:10.1128/mbio.01311-24 peripheral peptidoglycan synthesis Supports DivIVA control of ovococcal wall remodeling and elongation.
• peripheral peptidoglycan contributes to ellipsoid geometry RO:0002326

  Peripheral wall insertion contributes to elongation of the ellipsoidal cell body.

  • DOI:10.1128/mbio.01311-24 septum cleavage and peripheral peptidoglycan synthesis Supports peripheral PG as a remodeling event for ovococcal elongation.
• septal and peripheral peptidoglycan synthesis causes ellipsoid geometry biolink:causes

  Coordinated septal and peripheral synthesis shapes the ellipsoidal cell body.

  • DOI:10.1016/j.cub.2021.04.041 dynamics of peptidoglycan assembly Supports PG assembly dynamics in ovoid bacteria.
• ellipsoid geometry manifests as ellipsoidal METPO:2007400

  Ellipsoid cell-body geometry manifests the ellipsoidal trait.

  • DOI:10.1089/mdr.2014.0032 ovococci that are ellipsoid Supports the morphology endpoint.
• divisome (FtsZ/PBP2x/FtsW) carries out septal peptidoglycan synthesis

  The divisome (FtsZ/bPBP2x/FtsW) carries out septal PG synthesis.

  • DOI:10.1111/mmi.14659 an inner sPG machine (bPBP2x TP with FtsW GT)
• elongasome (PBP2b/RodA) carries out peripheral peptidoglycan synthesis

  The elongasome (bPBP2b/RodA plus Rod complex) carries out peripheral PG synthesis.

  • DOI:10.1111/mmi.14659 an outer pPG machine (bPBP2b TP with RodA GT plus Rod complex proteins)
• PBP2b required for peripheral peptidoglycan synthesis

  PBP2b is indispensable for lateral/peripheral PG synthesis and elongasome function.

  • DOI:10.1111/mmi.13543 PBP2b is identified as indispensable for lateral PG synthesis and is a key component of the elongasome
• spatial separation of septal and peripheral PG rings enables combined septal and peripheral PG synthesis RO:0002327

  Spatial separation of inner sPG and outer pPG rings enables concurrent septal and peripheral synthesis underlying ellipsoidal shape.

  • DOI:10.1111/mmi.14659 septal and peripheral peptidoglycan synthesis are spatially separated at midcell into two concentric structures
• undecaprenyl phosphate (Und-P) preferentially required for septal peptidoglycan synthesis

  Septal PG synthesis is more sensitive to Und-P limitation than peripheral synthesis, so Und-P limitation favors elongation.

  • DOI:10.7554/eLife.75607 septal peptidoglycan synthesis is more sensitive to reduced Und-P levels than peripheral peptidoglycan synthesis
• combined septal and peripheral PG synthesis results in ellipsoidal

  Ovococcal/ellipsoidal shape results from combined use of septal and peripheral PG synthesis.

  • DOI:10.1038/nrmicro3088 Ovococcal cells, with an ellipsoid shape... ovococci use both septal and peripheral peptidoglycan synthesis