fusiform shaped

Edge evidence

• graded polar peptidoglycan growth produces end-cap taper METPO:2000202

  Graded PG growth produces reduced end-cap radius.

  • DOI:10.1146/annurev-cellbio-101011-155745 polar growth Supports polar PG growth as the mechanism producing tapered ends.
• end-cap taper causes tapered geometry biolink:causes

  End-cap taper at both poles yields the fusiform body geometry.

  • DOI:10.1146/annurev-cellbio-101011-155745 cell shape is genetically determined Supports tapered geometry as a genetically determined shape outcome.
• tapered geometry manifests as fusiform shaped METPO:2007400

  Tapered geometry at both poles manifests the fusiform-shaped trait.

  • DOI:10.1111/1462-2920.13731 Fusobacterium nucleatum Supports fusiform morphology as the trait endpoint.
• MreB guides lateral peptidoglycan synthesis

  MreB filaments orient lateral PG synthesis to maintain rod-like cell shape.

  • DOI:10.1038/s41579-020-0366-3 MreB orients peptidoglycan synthesis to generate or maintain a smooth cylindrical rod shape.
• RodZ regulates MreB polymer localization/assembly RO:0002211

  RodZ modulates geometric localization and assembly of MreB.

  • DOI:10.1186/s12964-025-02373-y RodZ modulates geometric localization of MreB and is required for proper MreB cytoskeleton assembly.
• RodZ scaffolds elongasome complex

  RodZ provides a scaffold for the elongasome via MreB, RodA, PBP2, PBP1A/1B.

  • DOI:10.1038/s41579-020-0366-3 RodZ interacts with MreB, RodA, PBP2 and PBP1A/1B, providing a scaffold for the elongasome.
• MreC activates PBP2 RO:0002213

  MreC induces a structural change in PBP2 promoting its TPase activity.

  • DOI:10.1038/s41579-020-0366-3 MreC induces a structural change in PBP2, promoting PBP2 TPase and RodA GTase activity.
• RodA required for lateral peptidoglycan synthesis

  SEDS protein RodA with cognate bPBP mediates lateral PG incorporation.

  • DOI:10.1016/j.mib.2021.01.011 SEDS proteins RodA/FtsW with cognate bPBPs mediate lateral versus septal PG incorporation.
• FtsW required for septal peptidoglycan incorporation

  FtsW with cognate bPBP mediates septal PG incorporation.

  • DOI:10.1016/j.mib.2021.01.011 FtsW with cognate bPBP mediates septal PG incorporation.