spore shaped

Edge evidence

• forespore engulfment establishes mature spore body

  Engulfment establishes the forespore as a distinct spore body.

  • DOI:10.1146/annurev.genet.30.1.297 two-cell-chamber sporangium Supports spore morphogenesis through compartmental development.
• cortex formation builds layer of mature spore body

  Cortex formation builds a specialized spore structural layer.

  • DOI:10.1038/nrmicro2921 spore surface layers Supports specialized spore layers as components of mature morphology.
• coat assembly builds layer of mature spore body

  Coat assembly builds the multilayered external spore structure.

  • DOI:10.1038/nrmicro2921 mechanisms of coat assembly Supports coat assembly as a morphogenetic process.
• dehydrated spore core contributes to mature spore body RO:0002326

  Core dehydration contributes to mature spore architecture and resistance.

  • DOI:10.1111/j.1365-2672.2005.02736.x resistance of spores of Bacillus species Supports spore core properties as part of resistant spore morphology.
• mature spore body manifests as spore shaped METPO:2007400

  Mature spore-body architecture manifests the spore-shaped trait.

  • DOI:10.1038/nrmicro2921 highly resistant dormant cell type known as the spore Supports the trait endpoint.
• Spo0A phosphorylation positively regulates sporulation initiation

  Phosphorylation of the master regulator Spo0A initiates sporulation.

  • DOI:10.1126/sciadv.adq0791 Spo0A is the master regulator governing entry into sporulation; sporulation initiates upon phosphorylation of Spo0A (generalized across endospore formers).
• starvation positively regulates sporulation initiation

  Starvation triggers entry into the sporulation differentiation program.

  • DOI:10.1126/sciadv.adq0791 Starvation triggers bacterial spore formation, a committed differentiation program.
• sporulation initiation leads to forespore engulfment

  Sporulation initiation leads to forespore engulfment.

  • DOI:10.1126/sciadv.adq0791 Sporulation is a committed differentiation program proceeding through forespore engulfment.
• SpoIVA anchors spore coat

  SpoIVA anchors/tethers coat material to the spore surface (outer forespore membrane).

  • DOI:10.1038/nrmicro2921 SpoIVA functions to anchor coat material to the spore surface; required to tether the coat to the outer forespore membrane (conserved role).
• SpoVM required for spore encasement

  SpoVM is required for the morphological transition that encases the forespore.

  • DOI:10.1038/nrmicro2921 SpoVM and SpoVID are required for the morphological transition from a single scaffold cap to a full spherical shell that encases the forespore.
• SpoVID required for spore encasement

  SpoVID is required for spore encasement; mutants block formation of a full coat shell.

  • DOI:10.1038/nrmicro2921 SpoVID is explicitly required for spore encasement; spoVID mutants block formation of a full coat shell.
• CotE required for assembly of outer coat

  CotE is required for assembly of the spore outer coat.

  • DOI:10.1038/nrmicro2921 SafA is necessary for inner coat assembly and CotE for outer coat assembly.
• SafA required for assembly of inner coat

  SafA is required for assembly of the spore inner coat.

  • DOI:10.1038/nrmicro2921 SafA is necessary for inner coat assembly; SafA and CotE are respectively required for the deposition of the inner and outer coat.