pressure range

Edge evidence

• hydrostatic pressure defines pressure range METPO:2007500

  The hydrostatic-pressure axis defines the min/max bounds bracketed by the pressure range.

  • DOI:10.3389/fmolb.2022.1058381 Pressure-adaptation review frames the bounded span of growth-permissive pressure as a defining quantitative descriptor.
• pressure range associated with growth-permissive pressure span biolink:associated_with

  The pressure range records the bounded interval of permissive hydrostatic pressures.

  • DOI:10.1099/ijsem.0.001671 Colwellia marinimaniae MTCD1 illustrates a bounded growth-supporting pressure span (80-140 MPa).
• polyunsaturated fatty acid biosynthesis increases membrane fluidity under high hydrostatic pressure RO:0002213

  PUFA biosynthesis increases membrane fluidity to counter pressure-induced membrane ordering.

  • DOI:10.3389/fmolb.2022.1058381 PUFAs (C20:5, C22:6) associated with adaptation to high hydrostatic pressure; broad mechanism across taxa.
• unsaturated membrane lipids positively regulates pressure range

  Unsaturated membrane lipids support growth across high hydrostatic pressures.

  • DOI:10.3389/fmolb.2022.1058381 Mutants with reduced C18:1 could not withstand high pressure; unsaturation counters pressure ordering.
• membrane fluidity under high hydrostatic pressure expands pressure range

  Maintaining membrane fluidity under pressure expands the growth-supporting pressure range.

  • DOI:10.3390/microorganisms11071629 Pressure compacts membranes; organisms restore membrane disorder/function via unsaturation to sustain growth.
• trimethylamine N-oxide (TMAO) stabilizes protein stabilization via preferential hydration

  TMAO stabilizes proteins via preferential hydration (preferential exclusion from hydration layer).

  • DOI:10.1021/acs.chemrev.3c00432 TMAO preferentially excluded from protein hydration layer causing preferential hydration; biophysical mechanism, not microbe-specific.
• compatible solute accumulation stabilizes protein stabilization via preferential hydration

  Compatible solutes stabilize proteins via preferential hydration.

  • DOI:10.3390/microorganisms11071629 Compatible solutes (glutamate, betaine, beta-hydroxybutyrate) act by preferential hydration, displacing protein-bound water.