sulfur globule

Edge evidence

• oxidative sulfur metabolism produces elemental sulfur METPO:2000202

  Oxidation of reduced sulfur compounds generates elemental sulfur as an intermediate.

  • DOI:10.1016/S0065-2911(08)00002-7 Frigaard & Dahl describe sulfur globules as sulfur-storage intermediates formed during oxidative sulfur metabolism.
• elemental sulfur located in sulfur globule biolink:located_in

  The deposited elemental sulfur forms a globule inclusion.

  • DOI:10.1038/s41579-020-0413-0 Greening & Lithgow include sulfur globules among bacterial intracellular storage inclusions.
• sulfide:quinone oxidoreductase (SQR) produces sulfane sulfur METPO:2000202

  SQR-catalyzed oxidation of sulfide generates sulfane sulfur intermediates.

  • DOI:10.3390/ijms252010962 Initial oxidation of sulfide occurs under the action of SQR, producing sulfane sulfur; generalizes broadly to intracellular sulfur oxidizers.
• sulfide:quinone oxidoreductase (SQR) produces polysulfide (H2Sn) METPO:2000202

  SQR oxidizes sulfide to short-chain inorganic polysulfide (H2Sn, n>=2).

  • DOI:10.1128/aem.01941-21 SQR oxidized H2S into short-chain inorganic polysulfide (H2Sn, n >= 2); broad sulfur-chemistry mechanism.
• polysulfide (H2Sn) precursor of sulfur globule

  Polysulfide/sulfane sulfur spontaneously generates S8 that aggregates into sulfur globules.

  • DOI:10.1128/aem.01941-21 SQR oxidized H2S to H2Sn, which spontaneously generated S8; S8 aggregated into sulfur globules.
• persulfide dioxygenase (PDO) oxidizes sulfite METPO:2000016

  PDO oxidizes glutathione persulfide (GSSH) to sulfite (GSSH + O2 + H2O -> GSH + SO3^2- + 2H+).

  • DOI:10.3390/ijms252010962 PDO acts on GSSH: GSSH + O2 + H2O -> GSH + SO3^2- + 2H+; well-defined enzymatic edge.