temperature optimum

Edge evidence

• ambient temperature regulates membrane fluidity RO:0002211

  Ambient temperature sets a target membrane fluidity that the cell must match.

  • DOI:10.1146/annurev-micro-091313-103612 more unsaturated fatty acids Supports temperature as the input to membrane-fluidity adaptation.
• homoviscous lipid composition regulates membrane fluidity RO:0002211

  Homoviscous lipid composition maintains target membrane fluidity at the optimum temperature.

  • DOI:10.1146/annurev-micro-091313-103612 more unsaturated fatty acids Supports homoviscous adaptation as the mechanism setting membrane fluidity.
• ambient temperature regulates enzyme kinetics RO:0002211

  Ambient temperature scales enzyme turnover rates across the cellular network.

  • DOI:10.1016/s0300-9629(97)00003-0 energy transducing enzymes Supports temperature as the determinant of enzyme function in adapted organisms.
• enzyme kinetics enables maximal growth rate RO:0002327

  Adequately fast enzyme kinetics enable peak growth at the optimal temperature.

  • DOI:10.1016/s0300-9629(97)00003-0 adapted to environments of high temperature Supports balanced enzyme kinetics at adapted temperature as the basis of peak growth.
• maximal growth rate manifests as temperature optimum METPO:2007400

  The ambient temperature supporting peak growth manifests the temperature-optimum phenotype.

  • DOI:10.1016/s0300-9629(97)00003-0 adapted to environments of high temperature Supports the trait endpoint.
• homeoviscous adaptation regulates membrane fluidity RO:0002211

  Homeoviscous adaptation remodels membrane lipids to maintain target fluidity across temperatures.

  • DOI:10.1007/s42770-023-01057-4 Broad bacterial review: 'to maintain membrane fluidity at low temperature organisms alter membrane lipid composition (homeoviscous adaptation)'.
• membrane fluidity enables maximal growth rate RO:0002327

  Membrane physical state (fluidity) is a proximal determinant of growth, constraining transport, signaling, and division required for peak growth.

  • DOI:10.1007/s42770-023-01057-4 Membrane fluidity maintenance via homeoviscous adaptation supports the cellular processes underlying growth across the temperature range.
• Arrhenius plot deviation from linearity indicates stress / non-physiological growth regime

  Deviation from Arrhenius linearity in growth-rate-vs-temperature data marks a stress / non-physiological growth regime, bounding the optimum.

  • DOI:10.37256/amtt.5220244537 'Arrhenius plots, with linear regions indicating physiological growth and deviations indicating stress'.