temperature optimum mid2
METPO:1000444 · CLASS · REVIEWED
A temperature optimum phenotype with the best-growth ambient temperature between approximately 27 and 30 °C, characteristic of mesophilic physiology.
Temperature-optimum-mid2 mesophile setpoint
Edge evidence
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mesophilic environment
engages
baseline mesophile adaptation
Mesophilic environments engage baseline mesophile adaptation.
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DOI:10.1146/annurev-micro-091313-103612more unsaturated fatty acids
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baseline mesophile adaptation
produces
temperature optimum mid2
METPO:2000202Baseline mesophile adaptation yields a 27–30 °C optimum.
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DOI:10.1146/annurev-micro-091313-103612more unsaturated fatty acids
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temperature optimum mid2
is a
temperature optimum
rdfs:subClassOfTemperature optimum mid2 is a quantitative bin of the temperature-optimum phenotype.
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DOI:10.1016/s0300-9629(97)00003-0adapted to environments of high temperature
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temperature decrease
causes
membrane rigidification
biolink:causesA temperature drop rigidifies and thickens the cytoplasmic membrane.
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DOI:10.1128/spectrum.03925-23
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unsaturated fatty acids
increases
membrane fluidity
RO:0002213Higher unsaturated fatty acid content fluidizes and thins the bilayer.
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DOI:10.1007/s42770-023-01057-4
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baseline mesophile adaptation
increases
unsaturated fatty acids
RO:0002213Homeoviscous mesophile adaptation raises unsaturated fatty acid content to offset cooling.
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DOI:10.1007/s42770-023-01057-4
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membrane fluidity
enables
baseline mesophile adaptation
RO:0002327Maintained membrane fluidity supports the baseline mesophile physiological state.
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DOI:10.1128/spectrum.03925-23
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temperature optimum mid2
subclass of
mesophile category
The 27-30 C optimum falls within the mesophile growth range.
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DOI:10.1007/s42770-023-01057-4
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Provenance
- Source
- METPO (2025-11-25)
- Definition source
- DOI:10.1146/annurev-micro-091313-103612
Parent traits (1)
Synonyms (2)
- Mesophilie
- TO_27_to_30
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1000444[-3.661, -4.062, -0.551, +2.283, …]
Nearest neighbors in embedding space
- environment NaCl range low 0.746
- environment NaCl range mid1 0.728
- environment NaCl range mid2 0.661
- environment NaCl delta mid2 0.632
- environment pH range mid3 0.597
- environment temperature range mid1 0.596
- environment pH range mid2 0.595
- environment pH range low 0.595
Curation history
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SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_CAUSAL_GRAPH · claude
Added DOI-backed definition and causal graph linking baseline mesophile adaptation to the temperature-optimum-mid2 bin.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1, rdfs:subClassOf×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 5 evidence-backed generic edges (5 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 4 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002213×2, biolink:causes×1, RO:0002327×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007505×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:27208×1).