orange pigmented
METPO:1003026 · CLASS · REVIEWED
A pigmentation phenotype in which microbial colonies or cells appear orange due to production and accumulation of orange pigments such as carotenoids.
Orange pigmentation carotenoid mechanism
Edge evidence
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Crt enzymes
catalyzes
carotenoid biosynthesis
biolink:catalyzesCrt enzymes catalyze bacterial carotenoid biosynthetic reactions.
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DOI:10.1080/1040841X.2025.2526423crt genes ... reactions they catalyze
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carotenoid biosynthesis
produces
orange carotenoids
METPO:2000202Carotenoid biosynthesis produces orange pigments in representative bacteria.
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DOI:10.1080/1040841X.2025.2526423orange ... pigmentation in bacteria
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carotenoid biosynthesis
produces
staphyloxanthin
METPO:2000202The S. aureus carotenoid pathway produces staphyloxanthin.
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DOI:10.1128/JB.147.3.900-913.1981triterpenoid carotenoids possessing a C30 chain
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orange carotenoids
causes
visible orange color
biolink:causesOrange carotenoids cause visible orange pigmentation.
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DOI:10.1080/1040841X.2025.2526423responsible for ... orange ... pigmentation
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visible orange color
manifests as
orange pigmented
METPO:2007400Visible orange color manifests the orange-pigmented phenotype.
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DOI:10.1080/1040841X.2025.2526423orange ... pigmentation in bacteria
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lycopene beta-cyclase (CrtY)
converts
lycopene
CrtY lycopene beta-cyclase acts on lycopene as substrate.
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DOI:10.3390/microorganisms11030614
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lycopene
is converted to
beta-carotene
Lycopene cyclization yields orange beta-carotene.
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DOI:10.3390/microorganisms11030614
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beta-carotene hydroxylase (CrtZ)
converts
beta-carotene
CrtZ beta-carotene hydroxylase acts on beta-carotene.
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DOI:10.3390/microorganisms11030614
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beta-carotene
is converted to
zeaxanthin
Hydroxylation of beta-carotene yields zeaxanthin.
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DOI:10.3390/microorganisms11030614
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carotenoid ketolase (CrtW)
contributes to
ketocarotenoid biosynthesis
RO:0002326CrtW ketolase drives ketocarotenoid (e.g., canthaxanthin/astaxanthin) formation.
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DOI:10.3390/microorganisms11030614
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carotenoid accumulation
protects against
oxidative stress / reactive oxygen species
Accumulated carotenoids act as antioxidants neutralizing reactive oxygen species.
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DOI:10.7759/cureus.59892
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orange pigmented
has material basis in
carotenoid accumulation
The orange-pigmented phenotype is materially based on carotenoid accumulation.
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DOI:10.7759/cureus.59892
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Provenance
- Source
- METPO (2025-11-25)
- Definition source
- DOI:10.1080/1040841X.2025.2526423
Parent traits (1)
Synonyms (1)
- Pigment_orange
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1003026[-1.743, -2.814, -1.192, -0.288, …]
Nearest neighbors in embedding space
- morphology pigmentation 0.746
- morphology carotenoid pigmentation 0.710
- morphology red pigmented 0.697
- morphology pink pigmented 0.683
- morphology yellow pigmented 0.670
- morphology green pigmented 0.664
- morphology white pigmented 0.662
- morphology black pigmented 0.651
Curation history
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·
SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_WITH_LITERATURE · codex
Added DOI-backed definition and causal graph for Crt enzymes, carotenoid biosynthesis, orange carotenoids, staphyloxanthin, and visible orange color.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×2).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:catalyzes×1, biolink:causes×1).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007400×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0016117×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:71690×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 7 evidence-backed generic edges (9 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002326×1).
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GROUND_CAUSAL_NODES · claude
Grounded 3 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:15948×1, CHEBI:17579×1, CHEBI:27547×1).