yellow pigmented
METPO:1003030 · CLASS · REVIEWED
A pigmentation phenotype in which microbial colonies or cells appear yellow due to production of yellow pigments such as carotenoids.
Yellow pigmentation carotenoid mechanism
Edge evidence
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Crt enzymes
catalyzes
carotenoid biosynthesis
biolink:catalyzesCrt enzymes catalyze carotenoid biosynthetic reactions.
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DOI:10.1080/1040841X.2025.2526423crt genes ... reactions they catalyze
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carotenoid biosynthesis
produces
yellow carotenoids
METPO:2000202Carotenoid biosynthesis produces yellow-pigment carotenoids in representative bacteria.
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DOI:10.1080/1040841X.2025.2526423yellow pigmentation in bacteria
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yellow carotenoids
causes
visible yellow color
biolink:causesYellow carotenoids cause visible yellow colony or cell color.
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DOI:10.1016/j.tim.2010.07.007Carotenoids are natural pigments
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visible yellow color
manifests as
yellow pigmented
METPO:2007400Visible yellow color manifests the yellow-pigmented phenotype.
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DOI:10.1080/1040841X.2025.2526423yellow pigmentation in bacteria
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IPP/DMAPP
precursor of
geranylgeranyl diphosphate (GGPP)
C5 precursors IPP/DMAPP are elongated to the C20 carotenoid precursor GGPP.
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DOI:10.1038/s41598-024-58700-9
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IdsA/CrtE (GGPP synthase)
catalyzes
geranylgeranyl diphosphate (GGPP)
biolink:catalyzesIdsA/CrtE (GGPP synthase) catalyzes formation of GGPP from IPP and DMAPP.
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DOI:10.1038/s41598-024-58700-9
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geranylgeranyl diphosphate (GGPP)
precursor of
lycopene
Two GGPP molecules condense to form the C40 backbone lycopene.
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DOI:10.1038/s41598-024-58700-9
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CrtI (phytoene desaturase)
enables
lycopene biosynthesis
RO:0002327CrtI (phytoene desaturase) enables lycopene biosynthesis.
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DOI:10.3390/microorganisms12040803
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lycopene biosynthesis
produces
lycopene
METPO:2000202Lycopene biosynthesis produces lycopene.
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DOI:10.3390/microorganisms12040803
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CrtY (lycopene beta-cyclase)
catalyzes conversion to
beta-carotene
CrtY (lycopene beta-cyclase) cyclizes lycopene to beta-carotene.
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DOI:10.1038/s41598-024-58700-9
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beta-carotene
causes or contributes to
yellow pigmented
beta-carotene is a canonical yellow/orange carotenoid that contributes to the yellow phenotype.
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DOI:10.4014/jmb.2404.04018
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flexirubin-type pigment
contributes to
yellow pigmented
RO:0002326Flexirubin-type pigments produce yellow colony coloration, a carotenoid-independent yellow pigment route.
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DOI:10.1038/s41467-024-54112-5
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flexirubin-type pigment
protects against
reactive oxygen species damage
Flexirubin protects against reactive oxygen species damage.
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DOI:10.1038/s41467-024-54112-5
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Provenance
- Source
- METPO (2025-11-25)
- Definition source
- DOI:10.1080/1040841X.2025.2526423
Parent traits (1)
Synonyms (1)
- Pigment_yellow
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1003030[-3.392, -1.132, -2.360, -0.296, …]
Nearest neighbors in embedding space
- morphology pigmentation 0.749
- morphology carotenoid pigmentation 0.696
- morphology white pigmented 0.696
- morphology green pigmented 0.696
- morphology orange pigmented 0.670
- morphology pink pigmented 0.660
- morphology black pigmented 0.654
- morphology red pigmented 0.646
Curation history
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SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_WITH_LITERATURE · codex
Added DOI-backed definition and causal graph for Crt enzymes, carotenoid biosynthesis, yellow carotenoids, and visible yellow color.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×1).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:catalyzes×1, biolink:causes×1).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007400×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0016117×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 9 evidence-backed generic edges (10 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 4 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:catalyzes×1, RO:0002327×1, METPO:2000202×1, RO:0002326×1).
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GROUND_CAUSAL_NODES · claude
Grounded 3 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:15948×1, GO:1901177×1, CHEBI:17579×1).