ovoid shaped

METPO:1000677 · CLASS · REVIEWED

A cell shape in which an organism has an oval morphology, rounded at both ends with one end often slightly broader than the other.

Ovoid-shape midcell peptidoglycan mechanism

Evidence-backed causal sketch linking ovoid morphology to midcell peptidoglycan assembly, MapZ division-site placement, DivIVA-associated growth, and rounded ovoid geometry.

Ovoid-shape midcell peptidoglycan mechanism Interactive directed graph showing evidence-backed causal relationships for ovoid shaped.

Edge evidence

  • MapZ positions midcell peptidoglycan assembly

    MapZ participates in division-site placement for ovoid growth.

    • DOI:10.1016/j.mib.2016.07.014 relies on the membrane protein MapZ Supports MapZ as a division-positioning factor in S. pneumoniae.
  • midcell peptidoglycan assembly causes ovoid geometry biolink:causes

    Midcell peptidoglycan assembly shapes ovoid cell geometry.

    • DOI:10.1016/j.cub.2021.04.041 peptidoglycan synthesis ... in the ovoid bacterium Supports PG assembly dynamics in ovoid S. pneumoniae.
  • DivIVA controls septum splitting RO:0002211

    DivIVA controls septum splitting and elongation dynamics.

    • DOI:10.1128/mbio.01311-24 DivIVA controls the dynamics of septum splitting and cell elongation Supports DivIVA in ovococcal cell morphogenesis.
  • septum splitting contributes to ovoid geometry RO:0002326

    Septum splitting and elongation dynamics contribute to ovoid morphology.

    • DOI:10.1128/mbio.01311-24 how ovoid bacteria proliferate Supports septum/elongation dynamics as relevant to ovoid bacterial proliferation.
  • ovoid geometry manifests as ovoid shaped METPO:2007400

    Ovoid cell-body geometry manifests the ovoid-shaped trait.

    • DOI:10.1016/j.cub.2021.04.041 ovoid-shaped bacteria Supports the trait endpoint.
  • midcell peptidoglycan assembly has component septal peptidoglycan synthesis

    Ovococcal midcell growth includes a distinct septal PG synthesis mode.

    • DOI:10.1042/BSR20221664 There are two spatially distinct modes of PG synthesis: septal and peripheral.
  • midcell peptidoglycan assembly has component peripheral peptidoglycan synthesis

    Ovococcal midcell growth includes a distinct peripheral PG synthesis mode.

    • DOI:10.1042/BSR20221664 There are two spatially distinct modes of PG synthesis: septal and peripheral.
  • FtsZ treadmilling drives septal peptidoglycan synthesis

    FtsZ treadmilling drives septal PG synthesis.

    • DOI:10.1042/BSR20221664 FtsZ treadmilling drives septal PG synthesis together with the FtsW-PBP2x complex.
  • FtsW-PBP2x complex synthesizes septal peptidoglycan synthesis

    The FtsW-PBP2x complex synthesizes the division septum.

    • DOI:10.1042/BSR20221664 Septal PG synthesis is driven by the FtsW-PBP2x complex to synthesize the division septum.
  • RodA-PBP2b elongasome drives peripheral peptidoglycan synthesis

    The RodA-PBP2b elongasome drives peripheral PG synthesis.

    • DOI:10.1042/BSR20221664 Peripheral (elongation) activity is carried out by the elongasome, driven by the RodA-PBP2b pair.
  • MapZ positions FtsZ ring

    MapZ guides movement and positioning of the FtsZ ring.

    • DOI:10.1042/BSR20221664 MapZ guides movement of FtsZ and associated proteins from the septal ring to the equatorial ring.
  • midcell peptidoglycan assembly assembles as concentric midcell rings

    Septal and peripheral PG machineries assemble at midcell into concentric rings.

    • DOI:10.1042/BSR20221664 Septal and peripheral PG-synthesis machineries assemble at mid-cell into concentric rings (inner septal, outer peripheral).

Provenance

Source
METPO (2025-11-25)
Author
Luke Wang
Definition source
DOI:10.1016/j.cub.2021.04.041

Parent traits (1)

Synonyms (2)

  • S_ovoid RELATED_SYNONYM · metpo.owl
  • ovoid-shaped RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1000677 [+1.410, -5.519, -0.585, +0.196, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · CURATED_WITH_LITERATURE · codex

    Added DOI-backed definition and causal graph for MapZ, DivIVA, midcell peptidoglycan assembly, septum splitting, and ovoid cell geometry.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002326×1).

  4. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002211×1, METPO:2007400×1).

  5. · RENAME_PREDICATE_LABELS · claude

    Renamed 1 causal-edge predicate label(s) to align with existing groundings: shapes → causes ×1.

  6. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:causes×1).

  7. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (UniProtKB:Q1IYG2×1).

  8. · ENRICH_CAUSAL_GRAPH · claude

    Added 7 evidence-backed generic edges (7 new nodes) from the deep-research report.